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https://scholarbank.nus.edu.sg/handle/10635/34970
Title: | BIO-ASSAY USING LIQUID CRYSTALS | Authors: | YANG KUN-LIN XUE CHANGYING KHAN SAIF A. BI XINYAN |
Issue Date: | 18-Aug-2011 | Citation: | YANG KUN-LIN,XUE CHANGYING,KHAN SAIF A.,BI XINYAN (2011-08-18). BIO-ASSAY USING LIQUID CRYSTALS. ScholarBank@NUS Repository. | Abstract: | There is provided a method, an in vitro method and a detection system for detecting the presence of at least one biological molecule in at least one sample. The method can include, for example, providing a sample and/or a binding agent to a contact portion of a surface by way of at least one microfluidic channel; disposing a liquid crystal at the contact portion; determining whether the orientation of the liquid crystal changes after the sample contacts the binding agent, indicating the presence of the biological molecule; and determining length of bright region of the liquid crystal and/or change in interference color of said liquid crystal, and consequently indicating the quantity of said biological molecule. Also disclosed are methods of detecting biological molecules using at least one 4'-pentyl-biphenyl-4-R, where R may be at least one functional group selected from carboxylic acid, amine, aldehyde, and oligopeptide. | URI: | http://scholarbank.nus.edu.sg/handle/10635/34970 |
Appears in Collections: | Staff Publications |
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