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https://scholarbank.nus.edu.sg/handle/10635/32553
Title: | Use of des-aspartate-angiotensin I as an anti-cardiac hypertrophic agent | Authors: | SIM, MENG KWOON | Issue Date: | 30-Jun-1998 | Citation: | SIM, MENG KWOON (1998-06-30). Use of des-aspartate-angiotensin I as an anti-cardiac hypertrophic agent. ScholarBank@NUS Repository. | Abstract: | The use of des-Aspartate-angiotensin I (Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu) as an anti-cardiac hypertrophic agent is described. The compound, given either intravenously or orally, prevented the development of experimentally-induced cardiac hypertrophy in rats. Its action was dose-dependent and the maximum anti-cardiac hypertrophic effect was obtained at a dose of(i) 180 ng/day when given intravenously, and (ii) 285 .mu.g/day when given orally. | URI: | http://scholarbank.nus.edu.sg/handle/10635/32553 |
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