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https://scholarbank.nus.edu.sg/handle/10635/246262
| Title: | CLONAL ARCHITECTURE AND GENOMIC FEATURES OF SMOKING VERSUS NON-SMOKING ONCOGENE-DRIVEN NON-SMALL CELL LUNG CANCER IN EAST ASIA | Authors: | HUANG, CHEN-YANG | ORCID iD: |  orcid.org/0000-0002-6767-0389 |
Keywords: | oncogene-driven, non-small cell lung cancer, smoking signature, genomic study | Issue Date: | 21-Aug-2023 | Citation: | HUANG, CHEN-YANG (2023-08-21). CLONAL ARCHITECTURE AND GENOMIC FEATURES OF SMOKING VERSUS NON-SMOKING ONCOGENE-DRIVEN NON-SMALL CELL LUNG CANCER IN EAST ASIA. ScholarBank@NUS Repository. | Abstract: | Unlike smoking-related non-small cell lung cancers (NSCLCs), oncogene-driven NSCLCs are often characterized by low mutational burdens and complex genomic landscapes. However, the clonal architecture and genomic landscape of the oncogene-driven NSCLCs in smokers remain unknown. This thesis addresses an in-depth investigation of the impact of tobacco smoking on genomic and transcriptomic alterations by studying multi-regional exome and transcriptome data from 48 patients with NSCLCs. | URI: | https://scholarbank.nus.edu.sg/handle/10635/246262 |
| Appears in Collections: | Ph.D Theses (Open) |
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| File | Description | Size | Format | Access Settings | Version | |
|---|---|---|---|---|---|---|
| Final Thesis - Huang Chen-Yang 171023.pdf | 7.95 MB | Adobe PDF | OPEN | None | View/Download |
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