CLONAL ARCHITECTURE AND GENOMIC FEATURES OF SMOKING VERSUS NON-SMOKING ONCOGENE-DRIVEN NON-SMALL CELL LUNG CANCER IN EAST ASIA

Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/246262

DC Field	Value
dc.title	CLONAL ARCHITECTURE AND GENOMIC FEATURES OF SMOKING VERSUS NON-SMOKING ONCOGENE-DRIVEN NON-SMALL CELL LUNG CANCER IN EAST ASIA
dc.contributor.author	HUANG, CHEN-YANG
dc.date.accessioned	2023-11-30T18:00:41Z
dc.date.available	2023-11-30T18:00:41Z
dc.date.issued	2023-08-21
dc.identifier.citation	HUANG, CHEN-YANG (2023-08-21). CLONAL ARCHITECTURE AND GENOMIC FEATURES OF SMOKING VERSUS NON-SMOKING ONCOGENE-DRIVEN NON-SMALL CELL LUNG CANCER IN EAST ASIA. ScholarBank@NUS Repository.
dc.identifier.uri	https://scholarbank.nus.edu.sg/handle/10635/246262
dc.description.abstract	Unlike smoking-related non-small cell lung cancers (NSCLCs), oncogene-driven NSCLCs are often characterized by low mutational burdens and complex genomic landscapes. However, the clonal architecture and genomic landscape of the oncogene-driven NSCLCs in smokers remain unknown. This thesis addresses an in-depth investigation of the impact of tobacco smoking on genomic and transcriptomic alterations by studying multi-regional exome and transcriptome data from 48 patients with NSCLCs.
dc.language.iso	en
dc.subject	oncogene-driven, non-small cell lung cancer, smoking signature, genomic study
dc.type	Thesis
dc.contributor.department	DEAN'S OFFICE (DUKE-NUS)
dc.description.degree	Ph.D
dc.description.degreeconferred	DOCTOR OF PHILOSOPHY (DUKE)
dc.identifier.orcid	0000-0002-6767-0389
Appears in Collections:	Ph.D Theses (Open)

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