Please use this identifier to cite or link to this item:
https://doi.org/10.36660/abc.20201165
Title: | Plasma Ceramides in Cardiovascular Disease Risk Stratification | Authors: | Junqueira, Debora LM Stach, Alline Caixeta, Adriano Sallum, Juliana Yasaki, Erika Tsutsui, Jeane Rizatti, Edgar Rochitte, Carlos E Ching-Jianhong Kovalik, Jean-Paul Krieger, Jose E Richards, A Mark Chan, Mark Y de Carvalho, Leonardo P |
Keywords: | Science & Technology Life Sciences & Biomedicine Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology CORONARY-ARTERY-DISEASE HUMAN ATHEROSCLEROTIC PLAQUE SPHINGOLIPIDS ACCUMULATION METABOLISM ACTIVATION PATHWAY DEATH SCORE |
Issue Date: | 1-Jan-2022 | Publisher: | ARQUIVOS BRASILEIROS CARDIOLOGIA | Citation: | Junqueira, Debora LM, Stach, Alline, Caixeta, Adriano, Sallum, Juliana, Yasaki, Erika, Tsutsui, Jeane, Rizatti, Edgar, Rochitte, Carlos E, Ching-Jianhong, Kovalik, Jean-Paul, Krieger, Jose E, Richards, A Mark, Chan, Mark Y, de Carvalho, Leonardo P (2022-01-01). Plasma Ceramides in Cardiovascular Disease Risk Stratification. ARQUIVOS BRASILEIROS DE CARDIOLOGIA 118 (4) : 768-777. ScholarBank@NUS Repository. https://doi.org/10.36660/abc.20201165 | Abstract: | Ceramide production takes place throughout the body and plays a key role in the maintenance of normal physiology. However, ceramide levels are altered during disease states, particularly considering the development of diabetes and dyslipidemia. Ceramide production is also associated with atherosclerotic plaque instability. Recent studies revealed that patients with unstable coronary artery disease (CAD) presented increased plasma ceramide levels (especially C16, C18, and C24:1). These molecules are currently considered emerging biomarkers of cardiovascular diseases (CVD), being used for predicting atherosclerotic plaque instability and adverse cardiovascular events independently from traditional risk factors. With the aim of describing and discussing the role of ceramides in the stratification of cardiovascular diseases, this narrative review contextualizes the importance of this biomarker in the present cardiology scenario. | Source Title: | ARQUIVOS BRASILEIROS DE CARDIOLOGIA | URI: | https://scholarbank.nus.edu.sg/handle/10635/241792 | ISSN: | 0066-782X 1678-4170 |
DOI: | 10.36660/abc.20201165 |
Appears in Collections: | Staff Publications Elements |
Show full item record
Files in This Item:
File | Description | Size | Format | Access Settings | Version | |
---|---|---|---|---|---|---|
Plasma Ceramides in Cardiovascular Disease Risk Stratification.pdf | 1 MB | Adobe PDF | OPEN | None | View/Download |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.