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https://doi.org/10.1093/rpd/ncad053
Title: | A preliminary report on retrospective dose assessment by FISH translocation assay in FDNPP Nuclear Emergency Worker Study NEWS | Authors: | Yu Abe Miho Akiyama Kai Takebayashi Ryo Nakayama Valerie Swee Ting Goh Misaki Sugai-Takahashi Lobna Alkebsi Tomisato Miura Yumiko Suto Kotaro Ishii Osamu Kurihara Makoto Akashi Naohiro Tsuyama Akira Sakai Ken-ichi Kudo Yoshio Takashima |
Keywords: | Biological dosimetry Accident dosimetry |
Issue Date: | 3-Apr-2023 | Publisher: | Oxford University Press | Citation: | Yu Abe, Miho Akiyama, Kai Takebayashi, Ryo Nakayama, Valerie Swee Ting Goh, Misaki Sugai-Takahashi, Lobna Alkebsi, Tomisato Miura, Yumiko Suto, Kotaro Ishii, Osamu Kurihara, Makoto Akashi, Naohiro Tsuyama, Akira Sakai, Ken-ichi Kudo, Yoshio Takashima (2023-04-03). A preliminary report on retrospective dose assessment by FISH translocation assay in FDNPP Nuclear Emergency Worker Study NEWS. Radiation Protection Dosimetry : 1-5. ScholarBank@NUS Repository. https://doi.org/10.1093/rpd/ncad053 | Abstract: | In Japan, a national project of longitudinal health care and epidemiological research (NEWS) was developed in 2014 to analyze the effects of radiation on human health for workers who responded to the Fukushima Dai-ichi nuclear emergency in 2011. In 2018, peripheral blood for chromosome translocation analysis was collected from 62 workers. Retrospective dose assessment was performed with fluorescence in situ hybridization translocation (FISH-Tr) assay. The range of estimated doses by FISH-Tr assay was 0 - 635 mGy, in which 22 workers had estimated doses of more than 189 mGy. Biological dose estimates were five times higher in workers with physically measured total exposure recordings above 70 mGy. It is likely that smoking and medical exposure caused the discrepancy between estimated biological and physical total exposure doses. Thus, there is a possibility that retrospective biodosimetry assessment might over-estimate occupational exposures to workers exposed to chronic radiation during nuclear emergency work. | Source Title: | Radiation Protection Dosimetry | URI: | https://scholarbank.nus.edu.sg/handle/10635/241734 | ISSN: | 1742-3406 0144-8420 |
DOI: | 10.1093/rpd/ncad053 |
Appears in Collections: | Staff Publications |
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