Please use this identifier to cite or link to this item: https://doi.org/10.1186/s12955-020-01629-0
Title: Predicting EQ-5D-5L crosswalk from the PROMIS-29 profile for the United Kingdom, France, and Germany
Authors: Klapproth, Christoph Paul
van Bebber, J
Sidey-Gibbons, CJ
Valderas, JM 
Leplege, A
Rose, M
Fischer, F
Keywords: Science & Technology
Life Sciences & Biomedicine
Health Care Sciences & Services
Health Policy & Services
REPORTED OUTCOME MEASURES
QUALITY-OF-LIFE
ITEM BANKS
HEALTH-STATES
SHORT FORMS
SYSTEM
QUESTIONNAIRE
ALGORITHMS
PROMISA(R)
VALUATION
Issue Date: 17-Dec-2020
Publisher: BMC
Citation: Klapproth, Christoph Paul, van Bebber, J, Sidey-Gibbons, CJ, Valderas, JM, Leplege, A, Rose, M, Fischer, F (2020-12-17). Predicting EQ-5D-5L crosswalk from the PROMIS-29 profile for the United Kingdom, France, and Germany. HEALTH AND QUALITY OF LIFE OUTCOMES 18 (1). ScholarBank@NUS Repository. https://doi.org/10.1186/s12955-020-01629-0
Abstract: Background: EQ-5D health state utilities (HSU) are commonly used in health economics to compute quality-adjusted life years (QALYs). The EQ-5D, which is country-specific, can be derived directly or by mapping from self-reported health-related quality of life (HRQoL) scales such as the PROMIS-29 profile. The PROMIS-29 from the Patient Reported Outcome Measures Information System is a comprehensive assessment of self-reported health with excellent psychometric properties. We sought to find optimal models predicting the EQ-5D-5L crosswalk from the PROMIS-29 in the United Kingdom, France, and Germany and compared the prediction performances with that of a US model. Methods: We collected EQ-5D-5L and PROMIS-29 profiles and three samples representative of the general populations in the UK (n = 1509), France (n = 1501), and Germany (n = 1502). We used stepwise regression with backward selection to find the best models to predict the EQ-5D-5L crosswalk from all seven PROMIS-29 domains. We investigated the agreement between the observed and predicted EQ-5D-5L crosswalk in all three countries using various indices for the prediction performance, including Bland–Altman plots to examine the performance along the HSU continuum. Results: The EQ-5D-5L crosswalk was best predicted in France (nRMSEFRA = 0.075, nMAEFRA = 0.052), followed by the UK (nRMSEUK = 0.076, nMAEUK = 0.053) and Germany (nRMSEGER = 0.079, nMAEGER = 0.051). The Bland–Altman plots show that the inclusion of higher-order effects reduced the overprediction of low HSU scores. Conclusions: Our models provide a valid method to predict the EQ-5D-5L crosswalk from the PROMIS-29 for the UK, France, and Germany.
Source Title: HEALTH AND QUALITY OF LIFE OUTCOMES
URI: https://scholarbank.nus.edu.sg/handle/10635/236317
ISSN: 1477-7525
DOI: 10.1186/s12955-020-01629-0
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