Please use this identifier to cite or link to this item: https://doi.org/10.1186/s10195-021-00608-5
Title: Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study
Authors: Evans, Jonathan P
Maffulli, Nicola
Smith, Chris
Watts, Adam
Valderas, Jose 
Goodwin, Vicki
Keywords: Science & Technology
Life Sciences & Biomedicine
Orthopedics
Platelet-rich plasma
PRP
Consensus
Elbow
Tendinopathy
Tennis elbow
INJECTION THERAPIES
ADDITIONAL BENEFIT
EPICONDYLITIS
METAANALYSIS
TRIAL
Issue Date: 1-Dec-2021
Publisher: SPRINGER
Citation: Evans, Jonathan P, Maffulli, Nicola, Smith, Chris, Watts, Adam, Valderas, Jose, Goodwin, Vicki (2021-12-01). Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study. JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY 22 (1). ScholarBank@NUS Repository. https://doi.org/10.1186/s10195-021-00608-5
Abstract: Background: Platelet-rich plasma (PRP) is widely used in the management of lateral elbow tendinopathy (LET) despite conflicting evidence on its effectiveness. With high levels of user experience, this study aimed to assess consensus amongst experts on its clinical use. Methods: A three-round international Delphi study was conducted. Participants were invited through national society mailing lists and contact lists derived from a systematic search of the literature on PRP. In round one, a primary working group developed 40 statements on PRP preparation and clinical application. In rounds two and three, an international group of researchers on PRP and clinical users of the device scored their levels of agreement with the statements on a five-point scale. Consensus was defined as an interquartile range of ≤ 1. Results: Consensus of agreement was only reached for 17/40 (42.5%) statements. For statements on PRP formulation, consensus of agreement was reached in 2/6 statements (33%). Only limited consensus on the contraindications, delivery strategy and delivery technique was achieved. Conclusion: Experts reached very limited consensus on the use of PRP in LET. High levels of user experience have not resulted in a convergence of opinion on the technical components of PRP formulation and delivery, substantiating the need for further studies and improved trial reporting.
Source Title: JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
URI: https://scholarbank.nus.edu.sg/handle/10635/236307
ISSN: 1590-9921
1590-9999
DOI: 10.1186/s10195-021-00608-5
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