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Title: | The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms | Authors: | Khoury, Joseph D Solary, Eric Abla, Oussama Akkari, Yassmine Alaggio, Rita Apperley, Jane F Bejar, Rafael Berti, Emilio Busque, Lambert Chan, John KC Chen, Weina Chen, Xueyan Chng, Wee-Joo Choi, John K Colmenero, Isabel Coupland, Sarah E Cross, Nicholas CP De Jong, Daphne Elghetany, M Tarek Takahashi, Emiko Emile, Jean-Francois Ferry, Judith Fogelstrand, Linda Fontenay, Michaela Germing, Ulrich Gujral, Sumeet Haferlach, Torsten Harrison, Claire Hodge, Jennelle C Hu, Shimin Jansen, Joop H Kanagal-Shamanna, Rashmi Kantarjian, Hagop M Kratz, Christian P Li, Xiao-Qiu Lim, Megan S Loeb, Keith Loghavi, Sanam Marcogliese, Andrea Meshinchi, Soheil Michaels, Phillip Naresh, Kikkeri N Natkunam, Yasodha Nejati, Reza Ott, German Padron, Eric Patel, Keyur P Patkar, Nikhil Picarsic, Jennifer Platzbecker, Uwe Roberts, Irene Schuh, Anna Sewell, William Siebert, Reiner Tembhare, Prashant Tyner, Jeffrey Verstovsek, Srdan Wang, Wei Wood, Brent Xiao, Wenbin Yeung, Cecilia Hochhaus, Andreas |
Keywords: | Science & Technology Life Sciences & Biomedicine Oncology Hematology CHRONIC MYELOMONOCYTIC LEUKEMIA ROSAI-DORFMAN DISEASE CLONAL HEMATOPOIESIS ESSENTIAL THROMBOCYTHEMIA PROGNOSTIC-SIGNIFICANCE FLOW-CYTOMETRY DIAGNOSIS LANDSCAPE LYMPHOMA SARCOMA |
Issue Date: | 22-Jun-2022 | Publisher: | SPRINGERNATURE | Citation: | Khoury, Joseph D, Solary, Eric, Abla, Oussama, Akkari, Yassmine, Alaggio, Rita, Apperley, Jane F, Bejar, Rafael, Berti, Emilio, Busque, Lambert, Chan, John KC, Chen, Weina, Chen, Xueyan, Chng, Wee-Joo, Choi, John K, Colmenero, Isabel, Coupland, Sarah E, Cross, Nicholas CP, De Jong, Daphne, Elghetany, M Tarek, Takahashi, Emiko, Emile, Jean-Francois, Ferry, Judith, Fogelstrand, Linda, Fontenay, Michaela, Germing, Ulrich, Gujral, Sumeet, Haferlach, Torsten, Harrison, Claire, Hodge, Jennelle C, Hu, Shimin, Jansen, Joop H, Kanagal-Shamanna, Rashmi, Kantarjian, Hagop M, Kratz, Christian P, Li, Xiao-Qiu, Lim, Megan S, Loeb, Keith, Loghavi, Sanam, Marcogliese, Andrea, Meshinchi, Soheil, Michaels, Phillip, Naresh, Kikkeri N, Natkunam, Yasodha, Nejati, Reza, Ott, German, Padron, Eric, Patel, Keyur P, Patkar, Nikhil, Picarsic, Jennifer, Platzbecker, Uwe, Roberts, Irene, Schuh, Anna, Sewell, William, Siebert, Reiner, Tembhare, Prashant, Tyner, Jeffrey, Verstovsek, Srdan, Wang, Wei, Wood, Brent, Xiao, Wenbin, Yeung, Cecilia, Hochhaus, Andreas (2022-06-22). The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. LEUKEMIA 36 (7) : 1703-1719. ScholarBank@NUS Repository. https://doi.org/10.1038/s41375-022-01613-1 | Abstract: | The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database. This paper summarizes the new WHO classification scheme for myeloid and histiocytic/dendritic neoplasms and provides an overview of the principles and rationale underpinning changes from the prior edition. The definition and diagnosis of disease types continues to be based on multiple clinicopathologic parameters, but with refinement of diagnostic criteria and emphasis on therapeutically and/or prognostically actionable biomarkers. While a genetic basis for defining diseases is sought where possible, the classification strives to keep practical worldwide applicability in perspective. The result is an enhanced, contemporary, evidence-based classification of myeloid and histiocytic/dendritic neoplasms, rooted in molecular biology and an organizational structure that permits future scalability as new discoveries continue to inexorably inform future editions. | Source Title: | LEUKEMIA | URI: | https://scholarbank.nus.edu.sg/handle/10635/234469 | ISSN: | 0887-6924 1476-5551 |
DOI: | 10.1038/s41375-022-01613-1 |
Appears in Collections: | Staff Publications Elements |
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