Please use this identifier to cite or link to this item: https://doi.org/10.1038/s41598-021-94463-3
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dc.titleFactors influencing SARS-CoV-2 transmission and outbreak control measures in densely populated settings
dc.contributor.authorPung, Rachael
dc.contributor.authorLin, Bernard
dc.contributor.authorMaurer-Stroh, Sebastian
dc.contributor.authorSirota, Fernanda L.
dc.contributor.authorMak, Tze Minn
dc.contributor.authorOctavia, Sophie
dc.contributor.authorPang, Junxiong
dc.contributor.authorTan, Iain Beehuat
dc.contributor.authorTan, Clive
dc.contributor.authorOng, Biauw Chi
dc.contributor.authorCook, Alex R.
dc.contributor.authorTan, Doreen
dc.contributor.authorChua, Qin Xuan
dc.contributor.authorChong, Samuel Zeng Rong
dc.contributor.authorKoh, Han Fang
dc.contributor.authorYap, Elena
dc.contributor.authorSia, Priscilla
dc.contributor.authorTan, Ze Ren
dc.contributor.authorLee, Fong Sin
dc.contributor.authorGoh, Jun Kang Enan
dc.contributor.authorSuor, Peou Socheata Monica
dc.contributor.authorAng, Julian Xiao Li
dc.contributor.authorLee, Vernon J.
dc.date.accessioned2022-10-13T01:06:35Z
dc.date.available2022-10-13T01:06:35Z
dc.date.issued2021-07-27
dc.identifier.citationPung, Rachael, Lin, Bernard, Maurer-Stroh, Sebastian, Sirota, Fernanda L., Mak, Tze Minn, Octavia, Sophie, Pang, Junxiong, Tan, Iain Beehuat, Tan, Clive, Ong, Biauw Chi, Cook, Alex R., Tan, Doreen, Chua, Qin Xuan, Chong, Samuel Zeng Rong, Koh, Han Fang, Yap, Elena, Sia, Priscilla, Tan, Ze Ren, Lee, Fong Sin, Goh, Jun Kang Enan, Suor, Peou Socheata Monica, Ang, Julian Xiao Li, Lee, Vernon J. (2021-07-27). Factors influencing SARS-CoV-2 transmission and outbreak control measures in densely populated settings. Scientific Reports 11 (1) : 15297. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-021-94463-3
dc.identifier.issn2045-2322
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/232723
dc.description.abstractStarting with a handful of SARS-CoV-2 infections in dormitory residents in late March 2020, rapid transmission in their dense living environments ensued and by October 2020, more than 50,000 acute infections were identified across various dormitories in Singapore. The aim of the study is to identify combination of factors facilitating SARS-CoV-2 transmission and the impact of control measures in a dormitory through extensive epidemiological, serological and phylogenetic investigations, supported by simulation models. Our findings showed that asymptomatic cases and symptomatic cases who did not seek medical attention were major drivers of the outbreak. Furthermore, each resident had about 30 close contacts and each infected resident spread to 4.4 (IQR 3.5–5.3) others at the start of the outbreak. The final attack rate of the current outbreak was 76.2% (IQR 70.6–98.0%) and could be reduced by further 10% under a modified dormitory housing condition. These findings are important when designing living environments in a post COVID-19 future to reduce disease spread and facilitate rapid implementation of outbreak control measures. © 2021, The Author(s).
dc.publisherNature Research
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceScopus OA2021
dc.typeArticle
dc.contributor.departmentDEPT OF BIOLOGICAL SCIENCES
dc.contributor.departmentSAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.contributor.departmentDEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
dc.description.doi10.1038/s41598-021-94463-3
dc.description.sourcetitleScientific Reports
dc.description.volume11
dc.description.issue1
dc.description.page15297
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