Please use this identifier to cite or link to this item: https://doi.org/10.1186/s12885-021-08583-0
Title: Distinct employment interference profiles in patients with breast cancer prior to and for 12 months following surgery
Authors: Chan, Raymond Javan
Cooper, Bruce
Gordon, Louisa
Hart, Nicolas
Tan, Chia Jie
Koczwara, Bogda
Kober, Kord M.
Chan, Alexandre
Conley, Yvette P.
Paul, Steven M.
Miaskowski, Christine
Keywords: Employment interference
Fatigue
Female breast cancer
Patient-reported outcomes
Quality of life
Sleep disturbance
Issue Date: 2-Aug-2021
Publisher: BioMed Central Ltd
Citation: Chan, Raymond Javan, Cooper, Bruce, Gordon, Louisa, Hart, Nicolas, Tan, Chia Jie, Koczwara, Bogda, Kober, Kord M., Chan, Alexandre, Conley, Yvette P., Paul, Steven M., Miaskowski, Christine (2021-08-02). Distinct employment interference profiles in patients with breast cancer prior to and for 12 months following surgery. BMC Cancer 21 (1) : 883. ScholarBank@NUS Repository. https://doi.org/10.1186/s12885-021-08583-0
Rights: Attribution 4.0 International
Abstract: Purpose: To identify subgroups of female breast cancer patients with distinct self-reported employment interference (EI) profiles and determine which demographic, clinical, and symptom characteristics, and quality of life outcomes were associated with subgroup membership. Methods: Women with breast cancer (n = 385) were assessed for changes in EI over ten times, from prior to, through 12 months after breast cancer surgery. Latent profile analysis (LPA) was used to identify subgroups of patients with distinct EI profiles. Results: Three distinct EI profiles (i.e., None – 26.2% (n = 101), Low – 42.6% (n = 164), High – 31.2% (n = 120)) were identified. Compared to the None and Low groups, patients in the High group were more likely to be younger. Higher proportions in the High group were non-White, pre-menopausal prior to surgery, had more advanced stage disease, had received an axillary lymph node dissection, had received neoadjuvant chemotherapy, had received adjuvant chemotherapy, and had a re-excision or mastectomy on the affected breast within 6 months after surgery. In addition, these patients had lower quality of life scores. Compared to the None group, the High group had higher levels of trait and state anxiety, depressive symptoms, fatigue and sleep disturbance and lower levels of cognitive function. Conclusions: This study provides new knowledge regarding EI profiles among women in the year following breast cancer surgery. The non-modifiable risk factors (e.g., younger age, being non-White, having more advanced stage disease) can inform current screening procedures. The potentially modifiable risk factors can be used to develop interventions to improve employment outcomes of breast cancer patients. © 2021, The Author(s).
Source Title: BMC Cancer
URI: https://scholarbank.nus.edu.sg/handle/10635/232636
ISSN: 1471-2407
DOI: 10.1186/s12885-021-08583-0
Rights: Attribution 4.0 International
Appears in Collections:Students Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1186_s12885-021-08583-0.pdf616.16 kBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons