Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.drudis.2018.01.051
Title: Navigating albumin-based nanoparticles through various drug delivery routes
Authors: Tan, YL 
Ho, HK
Keywords: Albumins
Animals
Drug Administration Routes
Drug Carriers
Humans
Nanoparticles
Issue Date: 1-May-2018
Publisher: Elsevier BV
Citation: Tan, YL, Ho, HK (2018-05-01). Navigating albumin-based nanoparticles through various drug delivery routes. Drug Discovery Today 23 (5) : 1108-1114. ScholarBank@NUS Repository. https://doi.org/10.1016/j.drudis.2018.01.051
Abstract: As a natural polymer, albumin is well-received for being nontoxic, nonimmunogenic, biodegradable and biocompatible. Together with its targeting potential on specific cells, albumin-based nanoparticles appear as an effective carrier for various therapeutics. In recent years, there has been an increasing number of studies investigating the use of albumin-based nanoparticles across different administration routes. Although each route and target tissue presents a distinct anatomical and physiological profile that demands specific consideration, pharmaceuticals could still be delivered effectively via albumin-based nanoparticles. Therefore, this review discusses the features that warrant such applications across various delivery routes and explores their possibilities in other administration routes. The challenges associated with its use will also be elaborated to provide a holistic consideration to realise their clinical potentials.
Source Title: Drug Discovery Today
URI: https://scholarbank.nus.edu.sg/handle/10635/226978
ISSN: 13596446
18785832
DOI: 10.1016/j.drudis.2018.01.051
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
Navigating albumin-based nanoparticles through various drug delivery routes..pdfPublished version242.82 kBAdobe PDF

CLOSED

None

SCOPUSTM   
Citations

44
checked on Jan 26, 2023

Page view(s)

53
checked on Jan 26, 2023

Download(s)

1
checked on Jan 26, 2023

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.