Impact of Fibrin Glue Versus Suture Closure On Double-Headed Pterygia In Asian Eyes ? A 7-Year Study In A Tertiary Institution

Abstract

Background: To compare the recurrence rate and outcomes of double-headed pterygia using fibrin glue versus suture closure of conjunctival autograft. Methods: All patients with double-headed pterygia who underwent pterygia excision with conjunctival autograft from January 2012 to January 2019 in the National University Hospital of Singapore were included. Patients were divided into 2 groups depending on whether fibrin glue or sutures were used to secure the conjunctival autograft in place. All patients had a minimum of 6 months follow-up. Results: A total (26 patients) of 22 eyes had fibrin glue, while eight eyes underwent suture closure of their conjunctival autograft. Fibrin glue group had 4.5% recurrence rate, while suture group had 37.5% recurrence rate (p =.021). There is statistically significant improvement for overall visual acuity (p =.009) and cylinder (p =.002). There is also statistically significant improvement for visual acuity in the glue group (p =.026), but not in the suture group. Fibrin glue group had a shorter operation duration time compared to suture group (p <.001). There were no cases of graft dislocation, contraction or limbal stem cell deficiency. Conclusions: Low recurrence rates and good postoperative visual outcomes can be achieved with the split conjunctival autograft technique. Our study suggests that fibrin glue has an additional benefit over the use of sutures in the management of these complex cases.