Please use this identifier to cite or link to this item: https://doi.org/10.1021/acs.chemmater.0c01577
Title: Binary Organic Nanoparticles with Bright Aggregation-Induced Emission for Three-Photon Brain Vascular Imaging
Authors: Liu, Maixian
Gu, Bobo
Wu, Wenbo
Duan, Yukun 
Liu, Hongji
Deng, Xiangquan
Fan, Miaozhuang
Wang, Xiaomei
Wei, Xunbin
Yong, Ken-Tye
Wang, Ke
Xu, Gaixia
Liu, Bin 
Keywords: Science & Technology
Physical Sciences
Technology
Chemistry, Physical
Materials Science, Multidisciplinary
Chemistry
Materials Science
EXCITED-STATE DYNAMICS
QUANTUM-DOT-MICELLES
BIOCOMPATIBLE NANOPARTICLES
FLUORESCENT
MULTIPHOTON
Issue Date: 11-Aug-2020
Publisher: AMER CHEMICAL SOC
Citation: Liu, Maixian, Gu, Bobo, Wu, Wenbo, Duan, Yukun, Liu, Hongji, Deng, Xiangquan, Fan, Miaozhuang, Wang, Xiaomei, Wei, Xunbin, Yong, Ken-Tye, Wang, Ke, Xu, Gaixia, Liu, Bin (2020-08-11). Binary Organic Nanoparticles with Bright Aggregation-Induced Emission for Three-Photon Brain Vascular Imaging. CHEMISTRY OF MATERIALS 32 (15) : 6437-6443. ScholarBank@NUS Repository. https://doi.org/10.1021/acs.chemmater.0c01577
Abstract: Fluorogens with aggregation-induced emission (AIEgens) are promising optical agents for cellular and vascular imaging. AIEgens with bright emission in the far-red and near-infrared (NIR) regions are highly desirable, but the traditional strategies, i.e., introducing donor-acceptor (D-A) structures into AIEgens, generally lead to fluorogens with photoluminescence that is vulnerable to the polarity of the surrounding environment. In addition, because of the intrinsic rotor structure, AIEgens usually show absorption in the short-wavelength region, which is not optimized for imaging applications. In this contribution, we report binary organic nanoparticles (NPs) with tunable emission and high quantum efficiency in the red and far-red regions. By increasing the intermolecular distance, the obtained NPs offered enhanced luminescence quantum yields from 0.01 to 0.23 and increased three-photon excitation (3PE) cross sections, enabling high-quality and deep brain vascular imaging on an 8-week-old BALB/C mouse with up to 1.68 mm upon excitation at 1610 nm.
Source Title: CHEMISTRY OF MATERIALS
URI: https://scholarbank.nus.edu.sg/handle/10635/215197
ISSN: 08974756
15205002
DOI: 10.1021/acs.chemmater.0c01577
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
Binary Organic Nanoparticles with Bright Aggregation-Induced Emission for Three-Photon Brain Vascular Imaging.pdfSubmitted version816.84 kBAdobe PDF

OPEN

Post-printView/Download

SCOPUSTM   
Citations

27
checked on Jan 26, 2023

Page view(s)

99
checked on Jan 26, 2023

Download(s)

1
checked on Jan 26, 2023

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.