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Title: Geometric anisotropy on biomaterials surface for vascular scaffold design: Engineering and biological advances
Authors: Wang, Z.
Zhang, W.
Xie, C.
Wen, F.
Ma, C.
Lin, N.
Thian, E.S. 
Wang, X.
Keywords: Architecture
Blood vessel
Cell alignment
Tissue engineering
Issue Date: 2019
Publisher: IOP Publishing Ltd
Citation: Wang, Z., Zhang, W., Xie, C., Wen, F., Ma, C., Lin, N., Thian, E.S., Wang, X. (2019). Geometric anisotropy on biomaterials surface for vascular scaffold design: Engineering and biological advances. JPhys Materials 2 (3) : 32003. ScholarBank@NUS Repository.
Rights: Attribution 4.0 International
Abstract: Scaffold designs in combination with drug, growth factor and other bioactive chemicals account for lasting progress of vascular tissue engineering in the past decades. It is a great achievement to adjust tissue matrix composition and cell behaviour effectively. However, regenerating the innate physiologies of a blood vessel still needs its precise architecture to supply the vessel with structural basis for vascular functionality. Recent developments in biomaterial engineering have been explored in designing anisotropic surface geometries, and in turn to direct biological effects for recapitulating vascular tissue architecture. Here, we present current efforts, and propose future perspectives for the guidance on the architectural reconstruction and scaffold design of blood vessel. © 2019 The Author(s). Published by IOP Publishing Ltd
Source Title: JPhys Materials
ISSN: 2515-7639
DOI: 10.1088/2515-7639/ab1c68
Rights: Attribution 4.0 International
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