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Title: Toward Flexible Surface-Enhanced Raman Scattering (SERS) Sensors for Point-of-Care Diagnostics
Authors: Xu, K. 
Zhou, R.
Takei, K.
Hong, M. 
Keywords: flexible sensors
in situ detection
surface-enhanced Raman scattering
swab-sampling approach
tunable surface plasmon resonance
Issue Date: 2019
Publisher: John Wiley and Sons Inc
Citation: Xu, K., Zhou, R., Takei, K., Hong, M. (2019). Toward Flexible Surface-Enhanced Raman Scattering (SERS) Sensors for Point-of-Care Diagnostics. Advanced Science 6 (16) : 1900925. ScholarBank@NUS Repository.
Rights: Attribution 4.0 International
Abstract: Surface-enhanced Raman scattering (SERS) spectroscopy provides a noninvasive and highly sensitive route for fingerprint and label-free detection of a wide range of molecules. Recently, flexible SERS has attracted increasingly tremendous research interest due to its unique advantages compared to rigid substrate-based SERS. Here, the latest advances in flexible substrate-based SERS diagnostic devices are investigated in-depth. First, the intriguing prospect of point-of-care diagnostics is briefly described, followed by an introduction to the cutting-edge SERS technique. Then, the focus is moved from conventional rigid substrate-based SERS to the emerging flexible SERS technique. The main part of this report highlights the recent three categories of flexible SERS substrates, including actively tunable SERS, swab-sampling strategy, and the in situ SERS detection approach. Furthermore, other promising means of flexible SERS are also introduced. The flexible SERS substrates with low-cost, batch-fabrication, and easy-to-operate characteristics can be integrated into portable Raman spectroscopes for point-of-care diagnostics, which are conceivable to penetrate global markets and households as next-generation wearable sensors in the near future. © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Source Title: Advanced Science
ISSN: 2198-3844
DOI: 10.1002/advs.201900925
Rights: Attribution 4.0 International
Appears in Collections:Staff Publications

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