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Title: Anthropometric indices predicting incident hypertension in an Iranian population: The Isfahan cohort study
Authors: Sadeghi, M.
Talaei, M. 
Gharipour, M.
Oveisgharan, S.
Nezafati, P.
Dianatkhah, M.
Sarrafzadegan, N.
Keywords: Adiposity
Issue Date: 2019
Publisher: Turkish Society of Cardiology
Citation: Sadeghi, M., Talaei, M., Gharipour, M., Oveisgharan, S., Nezafati, P., Dianatkhah, M., Sarrafzadegan, N. (2019). Anthropometric indices predicting incident hypertension in an Iranian population: The Isfahan cohort study. Anatolian Journal of Cardiology 22 (1) : 33-43. ScholarBank@NUS Repository.
Rights: Attribution-NonCommercial 4.0 International
Abstract: Objective: The aim of the present study was to assess different obesity indices, as well as their best cut-off point, to predict the occurrence of hypertension (HTN) in an Iranian population. Methods: In a population-based study, subjects aged 35 years and older were followed for 7 years. Blood pressure was measured at baseline and after the follow-up. Anthropometry indices included body mass index (BMI), body adiposity index (BAI), the waist-to-height ratio (WHtR), the waist-to-hip ratio (WHpR), and waist and hip circumferences (WC and HC). Logistic regression was employed to calculate the odds ratio (OR) and 95% confidence intervals (CI) per standard deviation (SD) increment. The operating characteristic analysis was used to derive the best cut-off value for each index. Results: Among original 6504 participants, 2450 subjects who had no cardiovascular diseases (CVD) and HTN at baseline were revisited, and 542 (22.1%) new cases of HTN were detected. There were minimal differences between most indices in the adjusted models; however, the best HTN predictors were BMI (OR per SD 1.32; 95% CI 1.12-1.56) and almost equally WC (1.35; 1.13-1.60) in men and WC (1.20; 1.04-1.39) in women. As a binary predictor, BMI with a cut-off point of 24.9 kg/m2 in men (1.91; 1.40-2.62) and WC with a cut-off point of 98 cm in women (1.57; 1.17-2.10) were the best in adjusted models. WC, WHpR, and WHtR were significantly associated with an increased risk of HTN only in participants whose weight was normal (BMI, 18.5-24.9 kg/m2). Conclusion: Therefore, BMI in men and WC in women were the best predictors of HTN, both as continuous and binary factors at their appropriate cut-off points. (Anatol J Cardiol 2019; 22: 33-43). © Copyright 2019 by Turkish Society of Cardiology.
Source Title: Anatolian Journal of Cardiology
ISSN: 21492263
DOI: 10.14744/AnatolJCardiol.2019.10594
Rights: Attribution-NonCommercial 4.0 International
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