Please use this identifier to cite or link to this item: https://doi.org/10.3390/v11030250
Title: Diversity and evolution of viral pathogen community in cave nectar bats (eonycteris spelaea)
Authors: Mendenhall, I.H.
Wen, D.L.H. 
Jayakumar, J.
Gunalan, V.
Wang, L.
Mauer-Stroh, S.
Su, Y.C.F.
Smith, G.J.D.
Keywords: Adenovirus
Bunyavirus
Flavivirus
Herpesvirus
Metaviromics
Papillomavirus
Paramyxovirus
Parvovirus
Picornavirus
Polyomavirus
Poxvirus
Reovirus
Rotavirus
Southeast Asia
Issue Date: 2019
Publisher: MDPI AG
Citation: Mendenhall, I.H., Wen, D.L.H., Jayakumar, J., Gunalan, V., Wang, L., Mauer-Stroh, S., Su, Y.C.F., Smith, G.J.D. (2019). Diversity and evolution of viral pathogen community in cave nectar bats (eonycteris spelaea). Viruses 11 (3) : 250. ScholarBank@NUS Repository. https://doi.org/10.3390/v11030250
Rights: Attribution 4.0 International
Abstract: Bats are unique mammals, exhibit distinctive life history traits and have unique immunological approaches to suppression of viral diseases upon infection. High-throughput next-generation sequencing has been used in characterizing the virome of different bat species. The cave nectar bat, Eonycteris spelaea, has a broad geographical range across Southeast Asia, India and southern China, however, little is known about their involvement in virus transmission. Here we investigate the diversity and abundance of viral communities from a colony of Eonycteris spelaea residing in Singapore. Our results detected 47 and 22 different virus families from bat fecal and urine samples, respectively. Among these, we identify a large number of virus families including Adenoviridae, Flaviviridae, Reoviridae, Papillomaviridae, Paramyxoviridae, Parvoviridae, Picornaviridae, and Polyomaviridae. In most cases, viral sequences from Eonycteris spelaea are genetically related to a group of bat viruses from other bat genera (e.g., Eidolon, Miniopterus, Rhinolophus and Rousettus). The results of this study improve our knowledge of the host range, spread and evolution of several important viral pathogens. More significantly, our findings provide a baseline to study the temporal patterns of virus shedding and how they correlate with bat phenological trends. © 2019 MDPI AG. All rights reserved.
Source Title: Viruses
URI: https://scholarbank.nus.edu.sg/handle/10635/209589
ISSN: 1999-4915
DOI: 10.3390/v11030250
Rights: Attribution 4.0 International
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