Please use this identifier to cite or link to this item: https://doi.org/10.1002/sctm.17-0055
Title: Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles
Authors: Reiner, Agnes T
Witwer, Kenneth W
van Balkom, Bas WM
de Beer, Joel
Brodie, Chaya
Corteling, Randolph L
Gabrielsson, Susanne
Gimona, Mario
Ibrahim, Ahmed G
de Kleijn, Dominique
Lai, Charles P
Lotvall, Jan
del Portillo, Hernando A
Reischl, Ilona G
Riazifar, Milad
Salomon, Carlos
Tahara, Hidetoshi
Toh, Wei Seong 
Wauben, Marca HM
Yang, Vicky K
Yang, Yijun
Yeo, Ronne Wee Yeh
Yin, Hang
Giebel, Bernd
Rohde, Eva
Lim, Sai Kiang
Keywords: Science & Technology
Life Sciences & Biomedicine
Cell & Tissue Engineering
Cell Biology
Stem cells
Cellular therapy
Clinical trials
Clinical translation
Extracellular vesicles
Therapeutics
Exosomes
Microvesicles
Issue Date: 1-Aug-2017
Publisher: WILEY
Citation: Reiner, Agnes T, Witwer, Kenneth W, van Balkom, Bas WM, de Beer, Joel, Brodie, Chaya, Corteling, Randolph L, Gabrielsson, Susanne, Gimona, Mario, Ibrahim, Ahmed G, de Kleijn, Dominique, Lai, Charles P, Lotvall, Jan, del Portillo, Hernando A, Reischl, Ilona G, Riazifar, Milad, Salomon, Carlos, Tahara, Hidetoshi, Toh, Wei Seong, Wauben, Marca HM, Yang, Vicky K, Yang, Yijun, Yeo, Ronne Wee Yeh, Yin, Hang, Giebel, Bernd, Rohde, Eva, Lim, Sai Kiang (2017-08-01). Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles. STEM CELLS TRANSLATIONAL MEDICINE 6 (8) : 1730-1739. ScholarBank@NUS Repository. https://doi.org/10.1002/sctm.17-0055
Abstract: Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell-related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Vesicles and the Society for Clinical Research and Translation of Extracellular Vesicles Singapore convened a Workshop on this topic to discuss the opportunities and challenges associated with development of EV-based therapeutics at the preclinical and clinical levels. This review outlines topic-specific action items that, if addressed, will enhance the development of bestpractice models for EV therapies.
Source Title: STEM CELLS TRANSLATIONAL MEDICINE
URI: https://scholarbank.nus.edu.sg/handle/10635/206799
ISSN: 21576564
21576580
DOI: 10.1002/sctm.17-0055
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