Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jcyt.2020.05.002
Title: International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19
Authors: Boerger, Verena
Weiss, Daniel J
Anderson, Johnathon D
Borras, Francesc E
Bussolati, Benedetta
Carter, David RF
Dominici, Massimo
Falcon-Perez, Juan M
Gimona, Mario
Hill, Andrew F
Hoffman, Andrew M
Kleijn, Dominique de
Levine, Bruce L
Lim, Rebecca
Lotvall, Jan
Mitsialis, S Alex
Monguio-Tortajada, Marta
Muraca, Maurizio
Nieuwland, Rienk
Nowocin, Anna
O'Driscoll, Lorraine
Ortiz, Luis A
Phinney, Donald G
Reischl, Ilona
Rohde, Eva
Sanzenbacher, Ralf
Thery, Clotilde
Toh, Wei Seong 
Witwer, Kenneth W
Lim, Sai Kiang
Giebel, Bernd
Keywords: Science & Technology
Life Sciences & Biomedicine
Cell & Tissue Engineering
Biotechnology & Applied Microbiology
Cell Biology
Hematology
Medicine, Research & Experimental
Research & Experimental Medicine
STEM-CELLS
LUNG INJURY
EXOSOMES
HETEROGENEITY
MICROVESICLES
MODELS
Issue Date: 1-Sep-2020
Publisher: ELSEVIER SCI LTD
Citation: Boerger, Verena, Weiss, Daniel J, Anderson, Johnathon D, Borras, Francesc E, Bussolati, Benedetta, Carter, David RF, Dominici, Massimo, Falcon-Perez, Juan M, Gimona, Mario, Hill, Andrew F, Hoffman, Andrew M, Kleijn, Dominique de, Levine, Bruce L, Lim, Rebecca, Lotvall, Jan, Mitsialis, S Alex, Monguio-Tortajada, Marta, Muraca, Maurizio, Nieuwland, Rienk, Nowocin, Anna, O'Driscoll, Lorraine, Ortiz, Luis A, Phinney, Donald G, Reischl, Ilona, Rohde, Eva, Sanzenbacher, Ralf, Thery, Clotilde, Toh, Wei Seong, Witwer, Kenneth W, Lim, Sai Kiang, Giebel, Bernd (2020-09-01). International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19. CYTOTHERAPY 22 (9) : 482-485. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jcyt.2020.05.002
Abstract: STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular vesicles (EVs, including exosomes) from mesenchymal stromal cells (MSCs) and possibly other cell sources as treatments for COVID-19. Research and trials in this area are encouraged. However, ISEV and ISCT do not currently endorse the use of EVs or exosomes for any purpose in COVID-19, including but not limited to reducing cytokine storm, exerting regenerative effects or delivering drugs, pending the generation of appropriate manufacturing and quality control provisions, pre-clinical safety and efficacy data, rational clinical trial design and proper regulatory oversight.
Source Title: CYTOTHERAPY
URI: https://scholarbank.nus.edu.sg/handle/10635/206798
ISSN: 14653249
14772566
DOI: 10.1016/j.jcyt.2020.05.002
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