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https://doi.org/10.5588/ijtld.16.0123
| Title: | The clinical utility of Xpert® MTB/RIF testing in induced sputum | Authors: | Chew, MY Ng, J Cai, HM Lim, TG Lim, TK |
Keywords: | Adult Clinical Audit Humans Molecular Diagnostic Techniques Mycobacterium tuberculosis Prevalence Prospective Studies Sensitivity and Specificity Singapore Sputum Tuberculosis, Pulmonary |
Issue Date: | 1-Dec-2016 | Publisher: | International Union Against Tuberculosis and Lung Disease | Citation: | Chew, MY, Ng, J, Cai, HM, Lim, TG, Lim, TK (2016-12-01). The clinical utility of Xpert® MTB/RIF testing in induced sputum. International Journal of Tuberculosis and Lung Disease 20 (12) : 1668-1670. ScholarBank@NUS Repository. https://doi.org/10.5588/ijtld.16.0123 | Abstract: | We performed a prospective clinical audit in hospitalised patients with suspected pulmonary tuberculosis (PTB) with the objective of evaluating the accuracy and clinical utility of Xpert® MTB/RIF in induced sputum in an intermediate-burden setting. Of 450 patients audited, 61 (13.6%) were diagnosed with PTB based on positive culture. The sensitivity, specificity and positive and negative predictive values for Xpert in smear-negative cases for induced sputum were respectively 75%, 99.5%, 94.7% and 97.0%. Xpert in induced sputum may facilitate diagnostic yield and expedite treatment in up to a quarter of PTB patients. | Source Title: | International Journal of Tuberculosis and Lung Disease | URI: | https://scholarbank.nus.edu.sg/handle/10635/206796 | ISSN: | 10273719 18157920 |
DOI: | 10.5588/ijtld.16.0123 |
| Appears in Collections: | Staff Publications Elements |
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