Please use this identifier to cite or link to this item: https://doi.org/10.3389/fendo.2019.00630
Title: Adipsic Diabetes Insipidus—The Challenging Combination of Polyuria and Adipsia: A Case Report and Review of Literature
Authors: Dalan, R. 
Chin, H.
Hoe, J.
Chen, A.
Tan, H.
Boehm, B.O.
Chua, K.S.
Keywords: adipsia
diabetes insipidus
hypothalamus and neuroendocrinology
thirst and drinking
water balance
Issue Date: 2019
Publisher: Frontiers Media S.A.
Citation: Dalan, R., Chin, H., Hoe, J., Chen, A., Tan, H., Boehm, B.O., Chua, K.S. (2019). Adipsic Diabetes Insipidus—The Challenging Combination of Polyuria and Adipsia: A Case Report and Review of Literature. Frontiers in Endocrinology 10 : 630. ScholarBank@NUS Repository. https://doi.org/10.3389/fendo.2019.00630
Rights: Attribution 4.0 International
Abstract: Adipsic Diabetes Insipidus is a rare hypothalamic disorder characterized by a loss of thirst in response to hypernatraemia accompanied by diabetes insipidus. These occur secondary to a congregation of defects in the homeostatic mechanisms of water balance. A 27-year old Chinese female presented with Adipsic Diabetes Insipidus after cerebral arteriovenous malformation (AVM) surgery. Initial diagnosis and management was extremely challenging. Long term management required a careful interplay between low dose vasopressin analog treatment and fluids. Detailed charts of medication and sodium balance are described in the case presentation. We performed a literature search of similarly reported cases and describe the possible pathogenesis, etiology, clinical presentation, acute and chronic management, and prognosis. © Copyright © 2019 Dalan, Chin, Hoe, Chen, Tan, Boehm and Chua.
Source Title: Frontiers in Endocrinology
URI: https://scholarbank.nus.edu.sg/handle/10635/206289
ISSN: 1664-2392
DOI: 10.3389/fendo.2019.00630
Rights: Attribution 4.0 International
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_3389_fendo_2019_00630.pdf1 MBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons