Please use this identifier to cite or link to this item: https://doi.org/10.1055/s-0040-1718729
Title: The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease
Authors: Kim, HK
Tantry, US
Smith, SC
Jeong, MH
Park, SJ
Kim, MH
Lim, DS
Shin, ES
Park, DW
Huo, Y
Chen, SL
Bo, Z
Goto, S
Kimura, T
Yasuda, S
Chen, WJ
Chan, M 
Aradi, D
Geisler, T
Gorog, DA
Sibbing, D
Lip, GYH
Angiolillo, DJ
Gurbel, PA
Jeong, YH
Keywords: race
antiplatelet therapy
direct oral anticoagulants
ischemic risk
bleeding risk
Issue Date: 1-Apr-2021
Publisher: Georg Thieme Verlag KG
Citation: Kim, HK, Tantry, US, Smith, SC, Jeong, MH, Park, SJ, Kim, MH, Lim, DS, Shin, ES, Park, DW, Huo, Y, Chen, SL, Bo, Z, Goto, S, Kimura, T, Yasuda, S, Chen, WJ, Chan, M, Aradi, D, Geisler, T, Gorog, DA, Sibbing, D, Lip, GYH, Angiolillo, DJ, Gurbel, PA, Jeong, YH (2021-04-01). The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease. Thrombosis and Haemostasis 121 (4) : 422-432. ScholarBank@NUS Repository. https://doi.org/10.1055/s-0040-1718729
Abstract: East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during antithrombotic therapies compared with Caucasian patients. As potent P2Y 12 receptor inhibitors (e.g., ticagrelor and prasugrel) and direct oral anticoagulants are commonly used in current daily practice, the unique risk-benefit trade-off in East Asians has been a topic of emerging interest. In this article, we propose updated evidence and future directions of antithrombotic treatment in East Asian patients.
Source Title: Thrombosis and Haemostasis
URI: https://scholarbank.nus.edu.sg/handle/10635/205769
ISSN: 03406245
2567689X
DOI: 10.1055/s-0040-1718729
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