Please use this identifier to cite or link to this item: https://doi.org/10.7150/thno.39915
Title: Nanoparticle-based cell trackers for biomedical applications
Authors: Ni, J.-S.
Li, Y.
Yue, W.
Liu, B. 
Li, K.
Keywords: Aggregation-induced emission
Bioimaging
Cell tracking
Semiconducting polymer
Therapy
Issue Date: 2020
Publisher: Ivyspring International Publisher
Citation: Ni, J.-S., Li, Y., Yue, W., Liu, B., Li, K. (2020). Nanoparticle-based cell trackers for biomedical applications. Theranostics 10 (4) : 1923-1947. ScholarBank@NUS Repository. https://doi.org/10.7150/thno.39915
Rights: Attribution-NonCommercial 4.0 International
Abstract: The continuous or real-time tracking of biological processes using biocompatible contrast agents over a certain period of time is vital for precise diagnosis and treatment, such as monitoring tissue regeneration after stem cell transplantation, understanding the genesis, development, invasion and metastasis of cancer and so on. The rationally designed nanoparticles, including aggregation-induced emission (AIE) dots, inorganic quantum dots (QDs), nanodiamonds, superparamagnetic iron oxide nanoparticles (SPIONs), and semiconducting polymer nanoparticles (SPNs), have been explored to meet this urgent need. In this review, the development and application of these nanoparticle-based cell trackers for a variety of imaging technologies, including fluorescence imaging, photoacoustic imaging, magnetic resonance imaging, magnetic particle imaging, positron emission tomography and single photon emission computing tomography are discussed in detail. Moreover, the further therapeutic treatments using multi-functional trackers endowed with photodynamic and photothermal modalities are also introduced to provide a comprehensive perspective in this promising research field. © The author(s).
Source Title: Theranostics
URI: https://scholarbank.nus.edu.sg/handle/10635/198063
ISSN: 1838-7640
DOI: 10.7150/thno.39915
Rights: Attribution-NonCommercial 4.0 International
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