Please use this identifier to cite or link to this item: https://doi.org/10.3390/nu12123781
Title: Effects of anthocyanins in composite meals on cardiometabolic outcomes—a systematic review of randomized controlled feeding trials
Authors: Ou, J.L.S.
Yang, D. 
Liu, M.H. 
Keywords: Anthocyanin
Cardiovascular
Composite meal
Human nutritional intervention
Metabolic
Issue Date: 2020
Publisher: MDPI AG
Citation: Ou, J.L.S., Yang, D., Liu, M.H. (2020). Effects of anthocyanins in composite meals on cardiometabolic outcomes—a systematic review of randomized controlled feeding trials. Nutrients 12 (12) : 1-23. ScholarBank@NUS Repository. https://doi.org/10.3390/nu12123781
Rights: Attribution 4.0 International
Abstract: Accumulating epidemiological evidence suggests that anthocyanin intake is associated with reduced risks of cardiometabolic disorders, highlighting the importance of incorporating the phytochemical in our diets. Numerous food?based intervention studies have examined, in controlled meal settings, the role of anthocyanin on cardiometabolic health; but their effects have not been systematically summarized. This study aims to systematically review and summarize the effects of anthocyanin consumption with composite meals on cardiometabolic health from randomized controlled feeding trials. A systematic literature search for relevant human nutritional intervention studies was performed using PubMed, Embase, Cochrane Library, CINAHL Plus with Full Text, and Scopus databases. The Cochrane Risk of Bias tool was used to assess the study quality. Eighteen articles involving 371 participants were included in this review. Consistent improvements from anthocyanin intake were found in glycemic, gastric inhibitory peptide (GIP), interleukin?6 (IL? 6), and oxygen radical absorbance capacity (ORAC) responses. Anthocyanin intake did not significantly affect other markers of energy metabolism, vascular functions, oxidative stress and antioxidant status, as well as inflammatory responses. Inconsistencies in successful outcomes between epidemiological studies and included interventions were largely attributed to matrix effects, which may impede the bioaccessibility of anthocyanins and consequently, limiting its health benefits when co?delivered with some foods. © 2020 by the authors.
Source Title: Nutrients
URI: https://scholarbank.nus.edu.sg/handle/10635/196324
ISSN: 2072-6643
DOI: 10.3390/nu12123781
Rights: Attribution 4.0 International
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