Please use this identifier to cite or link to this item: https://doi.org/10.1039/d0sc02972f
Title: Access to substituted cyclobutenes by tandem [3,3]-sigmatropic rearrangement/[2 + 2] cycloaddition of dipropargylphosphonates under Ag/Co relay catalysis
Authors: Ni, Q.
Song, X. 
Png, C.W. 
Zhang, Y. 
Zhao, Y. 
Issue Date: 2020
Publisher: Royal Society of Chemistry
Citation: Ni, Q., Song, X., Png, C.W., Zhang, Y., Zhao, Y. (2020). Access to substituted cyclobutenes by tandem [3,3]-sigmatropic rearrangement/[2 + 2] cycloaddition of dipropargylphosphonates under Ag/Co relay catalysis. Chemical Science 11 (45) : 12329-12335. ScholarBank@NUS Repository. https://doi.org/10.1039/d0sc02972f
Rights: Attribution-NonCommercial 4.0 International
Abstract: We present herein an unconventional tandem [3,3]-sigmatropic rearrangement/[2 + 2] cycloaddition of simple dipropargylphosphonates to deliver a range of bicyclic polysubstituted cyclobutenes and cyclobutanes under Ag/Co relay catalysis. An interesting switch from allene-allene to allene-alkyne cycloaddition was observed based on the substitution of the substrates, which further diversified the range of compounds accessible from this practical method. Significantly, preliminary biological screening of these new compounds identified promising candidates as suppressors of cellular proliferation. This journal is © The Royal Society of Chemistry.
Source Title: Chemical Science
URI: https://scholarbank.nus.edu.sg/handle/10635/196284
ISSN: 2041-6520
DOI: 10.1039/d0sc02972f
Rights: Attribution-NonCommercial 4.0 International
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1039_d0sc02972f.pdf1.32 MBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

1
checked on Dec 8, 2022

Page view(s)

109
checked on Dec 1, 2022

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons