Please use this identifier to cite or link to this item: https://doi.org/10.14529/jsfi170201
Title: Using high performance computing to create and freely distribute the South Asian genomic database, necessary for precision medicine in this population
Authors: Shah, A.H
Picker, J.D
Jamuar, S.S 
Keywords: Database systems
Data Sharing
Disease treatment
Genetic variation
GgcINDIA
Global alliances
High performance computing
Individual variability
Natural variation
Genes
Issue Date: 2017
Publisher: Publishing center of the South Ural State University
Citation: Shah, A.H, Picker, J.D, Jamuar, S.S (2017). Using high performance computing to create and freely distribute the South Asian genomic database, necessary for precision medicine in this population. Supercomputing Frontiers and Innovations 4 (2) : 4-12. ScholarBank@NUS Repository. https://doi.org/10.14529/jsfi170201
Rights: Attribution 4.0 International
Abstract: Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Efforts to implement precision medicine have gained traction in recent years due to significantly increased understanding of the role of genetic variations in human disease over the past decade. However, delivery of precision medicine requires robust population specific reference genome datasets for full appreciation of existing natural variation. A large majority of publicly available genomic databases are primarily derived from Caucasian populations and do not fully address the diversity of Asian populations. In an effort to address this problem, we have aggregated and built a genomic database, ggcINDIA, specifically for South Asian populations. In collaboration with Global Alliance for Genomics and Health (GA4GH), we have made this database publicly available to the community through the GA4GH's Beacon project. ggcINDIA represents the first Beacon for South Asian populations. As more data are generated and aggregated, the ggcINDIA beacon will provide the precise genomic data that is critical to the delivery of precision medicine within South Asia. © The Authors 2016.
Source Title: Supercomputing Frontiers and Innovations
URI: https://scholarbank.nus.edu.sg/handle/10635/183864
ISSN: 2409-6008
DOI: 10.14529/jsfi170201
Rights: Attribution 4.0 International
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_14529_jsfi170201.pdf495.41 kBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons