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https://doi.org/10.3390/ijms19061721
| Title: | Potential clinical application of genomics in multiple myeloma | Authors: | Soekojo, C.Y de Mel, S Ooi, M Yan, B Chng, W.J |
Keywords: | circulating tumor cell comparative genomic hybridization exosome fluorescence in situ hybridization gene expression genetic disorder genomics karyotyping liquid biopsy metaphase minimal residual disease multiple myeloma next generation sequencing prognosis Review RNA sequence treatment response genetics human multiple myeloma pathology single cell analysis Genomics Humans Liquid Biopsy Multiple Myeloma Neoplasm, Residual Prognosis Single-Cell Analysis |
Issue Date: | 2018 | Publisher: | MDPI | Citation: | Soekojo, C.Y, de Mel, S, Ooi, M, Yan, B, Chng, W.J (2018). Potential clinical application of genomics in multiple myeloma. International Journal of Molecular Sciences 19 (6) : 1721. ScholarBank@NUS Repository. https://doi.org/10.3390/ijms19061721 | Rights: | Attribution 4.0 International | Abstract: | Multiple myeloma is a heterogeneous disease with different characteristics, and genetic aberrations play important roles in this heterogeneity. Studies have shown that these genetic aberrations are crucial in prognostication and response assessment; recent efforts have focused on their possible therapeutic implications. Despite many emerging studies being published, the best way to incorporate these results into clinical practice remains unclear. In this review paper we describe the different genomic techniques available, including the latest advancements, and discuss the potential clinical application of genomics in multiple myeloma. © 2018 by the authors. Licensee MDPI, Basel, Switzerland. | Source Title: | International Journal of Molecular Sciences | URI: | https://scholarbank.nus.edu.sg/handle/10635/183841 | ISSN: | 1661-6596 | DOI: | 10.3390/ijms19061721 | Rights: | Attribution 4.0 International |
| Appears in Collections: | Staff Publications Elements |
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