Please use this identifier to cite or link to this item: https://doi.org/10.3390/ijms19061721
Title: Potential clinical application of genomics in multiple myeloma
Authors: Soekojo, C.Y
de Mel, S
Ooi, M 
Yan, B
Chng, W.J 
Keywords: circulating tumor cell
comparative genomic hybridization
exosome
fluorescence in situ hybridization
gene expression
genetic disorder
genomics
karyotyping
liquid biopsy
metaphase
minimal residual disease
multiple myeloma
next generation sequencing
prognosis
Review
RNA sequence
treatment response
genetics
human
multiple myeloma
pathology
single cell analysis
Genomics
Humans
Liquid Biopsy
Multiple Myeloma
Neoplasm, Residual
Prognosis
Single-Cell Analysis
Issue Date: 2018
Publisher: MDPI
Citation: Soekojo, C.Y, de Mel, S, Ooi, M, Yan, B, Chng, W.J (2018). Potential clinical application of genomics in multiple myeloma. International Journal of Molecular Sciences 19 (6) : 1721. ScholarBank@NUS Repository. https://doi.org/10.3390/ijms19061721
Rights: Attribution 4.0 International
Abstract: Multiple myeloma is a heterogeneous disease with different characteristics, and genetic aberrations play important roles in this heterogeneity. Studies have shown that these genetic aberrations are crucial in prognostication and response assessment; recent efforts have focused on their possible therapeutic implications. Despite many emerging studies being published, the best way to incorporate these results into clinical practice remains unclear. In this review paper we describe the different genomic techniques available, including the latest advancements, and discuss the potential clinical application of genomics in multiple myeloma. © 2018 by the authors. Licensee MDPI, Basel, Switzerland.
Source Title: International Journal of Molecular Sciences
URI: https://scholarbank.nus.edu.sg/handle/10635/183841
ISSN: 1661-6596
DOI: 10.3390/ijms19061721
Rights: Attribution 4.0 International
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