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https://doi.org/10.2807/1560-7917.ES.2015.20.40.30035
| Title: | Genotypic anomaly in ebola virus strains circulating in magazine wharf Area, Freetown, Sierra Leone, 2015 | Authors: | Smits, S.L Pas, S.D Reusken, C.B Haagmans, B.L Pertile, P Cancedda, C Dierberg, K Wurie, I Kamara, A Kargbo, D Caddy, S.L Arias, A Thorne, L Lu, J Jah, U Goodfellow, I Koopmans, M.P |
Keywords: | Africa Article Ebola hemorrhagic fever Ebolavirus evolution genetic variability genome analysis haplotype human mutation nonhuman nucleotide sequence sequence alignment Sierra Leone virus genome virus strain Ebolavirus epidemic genetics genotype Hemorrhagic Fever, Ebola isolation and purification reverse transcription polymerase chain reaction Disease Outbreaks Ebolavirus Genome, Viral Genotype Hemorrhagic Fever, Ebola Humans Reverse Transcriptase Polymerase Chain Reaction Sierra Leone |
Issue Date: | 2015 | Citation: | Smits, S.L, Pas, S.D, Reusken, C.B, Haagmans, B.L, Pertile, P, Cancedda, C, Dierberg, K, Wurie, I, Kamara, A, Kargbo, D, Caddy, S.L, Arias, A, Thorne, L, Lu, J, Jah, U, Goodfellow, I, Koopmans, M.P (2015). Genotypic anomaly in ebola virus strains circulating in magazine wharf Area, Freetown, Sierra Leone, 2015. Eurosurveillance 20 (40). ScholarBank@NUS Repository. https://doi.org/10.2807/1560-7917.ES.2015.20.40.30035 | Rights: | Attribution 4.0 International | Abstract: | The Magazine Wharf area, Freetown, Sierra Leone was a focus of ongoing Ebola virus transmission from late June 2015. Viral genomes linked to this area contain a series of 13 T to C substitutions in a 150 base pair intergenic region downstream of viral protein 40 open reading frame, similar to the Ebolavirus/H.sapienswt/ SLE/2014/Makona-J0169 strain (J0169) detected in the same town in November 2014. This suggests that recently circulating viruses from Freetown descend from a J0169-like virus. @ 2015, European Centre for Disease Prevention and Control (ECDC). All rights reserved. | Source Title: | Eurosurveillance | URI: | https://scholarbank.nus.edu.sg/handle/10635/183746 | ISSN: | 1025496X | DOI: | 10.2807/1560-7917.ES.2015.20.40.30035 | Rights: | Attribution 4.0 International |
| Appears in Collections: | Elements Staff Publications |
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