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https://doi.org/10.1155/2015/928608
Title: | Effect of intraoperative corneal stromal pocket irrigation in small incision lenticule extraction | Authors: | Liu, Y.-C Jayasinghe, L Ang, H.P Lwin, N.C Yam, G.H.F Mehta, J.S |
Keywords: | animal experiment animal tissue anterior lamellar thickness Article confocal microscopy controlled study convalescence cornea thickness corneal stromal pocket irrigation excimer laser eye lavage follow up in vivo study intermethod comparison laser epithelial keratomileusis nonhuman ophthalmic femtosecond laser optical coherence tomography optical coherence tomography device peroperative care posterior lamellar thickness postoperative period preoperative period rabbit model refractive surgery slit lamp small incision lenticule extraction visual acuity visual system parameters animal comparative study cornea stroma keratomileusis lavage microsurgery multimodality cancer therapy pathology peroperative care procedures rabbit refractive surgery surgery treatment outcome Oryctolagus cuniculus Animals Combined Modality Therapy Corneal Stroma Intraoperative Care Keratomileusis, Laser In Situ Microsurgery Rabbits Refractive Surgical Procedures Therapeutic Irrigation Tomography, Optical Coherence Treatment Outcome |
Issue Date: | 2015 | Citation: | Liu, Y.-C, Jayasinghe, L, Ang, H.P, Lwin, N.C, Yam, G.H.F, Mehta, J.S (2015). Effect of intraoperative corneal stromal pocket irrigation in small incision lenticule extraction. BioMed Research International 2015 : 928608. ScholarBank@NUS Repository. https://doi.org/10.1155/2015/928608 | Rights: | Attribution 4.0 International | Abstract: | This study aimed at evaluating the effect of intraoperative corneal pocket irrigation in small incision lenticule extraction (SMILE) and compares it to that in femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Sixteen rabbit eyes underwent a SMILE procedure, with 8 eyes having corneal pocket irrigation, while the other 8 eyes were without irrigation. Another 16 eyes underwent a FS-LASIK procedure for comparison, with 8 eyes having flap irrigation, while the other 8 eyes were without irrigation. The results showed that the changes in the total corneal thickness, anterior and posterior lamellar thickness, measured by the anterior segment optical coherence tomography, were comparable between the SMILE with and without irrigation groups, suggesting that the irrigation did not lead to significant changes in the corneal thickness. However, at postoperative 8 hours, in vivo confocal microscopy showed that the interface reflectivity in the SMILE with irrigation group was significantly higher than that in other three groups. The presence of interface fluid was further confirmed by the identification of fluid pockets with undulated collagen shown on histological section in the post-SMILE with irrigation eyes. Our findings might contribute to the occurrence of post-SMILE delayed immediate visual quality recovery and further clinical study is required. © 2015 Yu-Chi Liu et al. | Source Title: | BioMed Research International | URI: | https://scholarbank.nus.edu.sg/handle/10635/183604 | ISSN: | 23146133 | DOI: | 10.1155/2015/928608 | Rights: | Attribution 4.0 International |
Appears in Collections: | Elements Staff Publications |
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