Please use this identifier to cite or link to this item: https://doi.org/10.1155/2015/928608
Title: Effect of intraoperative corneal stromal pocket irrigation in small incision lenticule extraction
Authors: Liu, Y.-C 
Jayasinghe, L
Ang, H.P
Lwin, N.C
Yam, G.H.F 
Mehta, J.S 
Keywords: animal experiment
animal tissue
anterior lamellar thickness
Article
confocal microscopy
controlled study
convalescence
cornea thickness
corneal stromal pocket irrigation
excimer laser
eye lavage
follow up
in vivo study
intermethod comparison
laser epithelial keratomileusis
nonhuman
ophthalmic femtosecond laser
optical coherence tomography
optical coherence tomography device
peroperative care
posterior lamellar thickness
postoperative period
preoperative period
rabbit model
refractive surgery
slit lamp
small incision lenticule extraction
visual acuity
visual system parameters
animal
comparative study
cornea stroma
keratomileusis
lavage
microsurgery
multimodality cancer therapy
pathology
peroperative care
procedures
rabbit
refractive surgery
surgery
treatment outcome
Oryctolagus cuniculus
Animals
Combined Modality Therapy
Corneal Stroma
Intraoperative Care
Keratomileusis, Laser In Situ
Microsurgery
Rabbits
Refractive Surgical Procedures
Therapeutic Irrigation
Tomography, Optical Coherence
Treatment Outcome
Issue Date: 2015
Citation: Liu, Y.-C, Jayasinghe, L, Ang, H.P, Lwin, N.C, Yam, G.H.F, Mehta, J.S (2015). Effect of intraoperative corneal stromal pocket irrigation in small incision lenticule extraction. BioMed Research International 2015 : 928608. ScholarBank@NUS Repository. https://doi.org/10.1155/2015/928608
Rights: Attribution 4.0 International
Abstract: This study aimed at evaluating the effect of intraoperative corneal pocket irrigation in small incision lenticule extraction (SMILE) and compares it to that in femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Sixteen rabbit eyes underwent a SMILE procedure, with 8 eyes having corneal pocket irrigation, while the other 8 eyes were without irrigation. Another 16 eyes underwent a FS-LASIK procedure for comparison, with 8 eyes having flap irrigation, while the other 8 eyes were without irrigation. The results showed that the changes in the total corneal thickness, anterior and posterior lamellar thickness, measured by the anterior segment optical coherence tomography, were comparable between the SMILE with and without irrigation groups, suggesting that the irrigation did not lead to significant changes in the corneal thickness. However, at postoperative 8 hours, in vivo confocal microscopy showed that the interface reflectivity in the SMILE with irrigation group was significantly higher than that in other three groups. The presence of interface fluid was further confirmed by the identification of fluid pockets with undulated collagen shown on histological section in the post-SMILE with irrigation eyes. Our findings might contribute to the occurrence of post-SMILE delayed immediate visual quality recovery and further clinical study is required. © 2015 Yu-Chi Liu et al.
Source Title: BioMed Research International
URI: https://scholarbank.nus.edu.sg/handle/10635/183604
ISSN: 23146133
DOI: 10.1155/2015/928608
Rights: Attribution 4.0 International
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