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https://doi.org/10.1186/gb-2008-9-1-r2
| Title: | High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae | Authors: | Lee, H.-G Lee, H.-S Jeon, S.-H Chung, T.-H Lim, Y.-S Huh, W.-K |
Keywords: | transcription factor analytic method article chromatin immunoprecipitation controlled study data analysis gene expression profiling gene expression regulation genetic regulation genetic transcription intermethod comparison protein determination protein motif regulatory mechanism reliability Saccharomyces cerevisiae transcription regulation gene regulatory network genetics Saccharomyces cerevisiae Gene Expression Profiling Gene Expression Regulation, Fungal Gene Regulatory Networks Saccharomyces cerevisiae |
Issue Date: | 2008 | Citation: | Lee, H.-G, Lee, H.-S, Jeon, S.-H, Chung, T.-H, Lim, Y.-S, Huh, W.-K (2008). High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae. Genome Biology 9 (1) : R2. ScholarBank@NUS Repository. https://doi.org/10.1186/gb-2008-9-1-r2 | Rights: | Attribution 4.0 International | Abstract: | We present an approach for identifying condition-specific regulatory modules by using separate units of gene expression profiles along with ChIP-chip and motif data from Saccharomyces cerevisiae. By investigating the unique and common features of the obtained condition-specific modules, we detected several important properties of transcriptional network reorganization. Our approach reveals the functionally distinct coregulated submodules embedded in a coexpressed gene module and provides an effective method for identifying various condition-specific regulatory events at high resolution. © 2008 Lee et al.; licensee BioMed Central Ltd. | Source Title: | Genome Biology | URI: | https://scholarbank.nus.edu.sg/handle/10635/183281 | ISSN: | 14747596 | DOI: | 10.1186/gb-2008-9-1-r2 | Rights: | Attribution 4.0 International |
| Appears in Collections: | Staff Publications Elements |
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