Please use this identifier to cite or link to this item: https://doi.org/10.1038/srep20723
Title: Dietary n-3 Fatty Acid, ?-Tocopherol, Zinc, Vitamin D, Vitamin C, and ?-carotene are Associated with Age-Related Macular Degeneration in Japan
Authors: Aoki, A
Inoue, M
Nguyen, E
Obata, R
Kadonosono, K
Shinkai, S
Hashimoto, H
Sasaki, S
Yanagi, Y 
Keywords: alpha tocopherol
ascorbic acid
beta carotene
omega 3 fatty acid
vitamin D
zinc
aged
caloric intake
case control study
dietary supplement
female
human
Japan
macular degeneration
male
questionnaire
risk factor
statistical model
very elderly
Aged
Aged, 80 and over
alpha-Tocopherol
Ascorbic Acid
beta Carotene
Case-Control Studies
Dietary Supplements
Energy Intake
Fatty Acids, Omega-3
Female
Humans
Japan
Logistic Models
Macular Degeneration
Male
Risk Factors
Surveys and Questionnaires
Vitamin D
Zinc
Issue Date: 2016
Publisher: Nature Publishing Group
Citation: Aoki, A, Inoue, M, Nguyen, E, Obata, R, Kadonosono, K, Shinkai, S, Hashimoto, H, Sasaki, S, Yanagi, Y (2016). Dietary n-3 Fatty Acid, ?-Tocopherol, Zinc, Vitamin D, Vitamin C, and ?-carotene are Associated with Age-Related Macular Degeneration in Japan. Scientific Reports 6 : 20723. ScholarBank@NUS Repository. https://doi.org/10.1038/srep20723
Rights: Attribution 4.0 International
Abstract: This case-control study reports the association between nutrient intake and neovascular age-related macular degeneration (AMD) in Japan. The nutrient intake of 161 neovascular AMD cases from two university hospitals and 369 population-based control subjects from a cohort study was assessed using a brief-Type self-Administered questionnaire on diet history, which required respondent recall of the usual intake of 58 foods during the preceding month. Energy-Adjusted nutrient intake values were compared between the groups. Logistic regression analysis was used to estimate odds ratios (ORs) and 95% CIs adjusted for smoking history, age, sex, chronic disease history, supplement use, and alcohol consumption. Logistic regression analysis demonstrated that low intakes of n-3 fatty acid, ?-Tocopherol, zinc, vitamin D, vitamin C, and ?-carotene were associated with neovascular AMD (Trend P < 0.0001 for n-3 fatty acid, Trend P < 0.0001 for ?-Tocopherol, Trend P < 0.0001 for zinc, Trend P = 0.002 for vitamin D, Trend P = 0.04 for vitamin C, Trend P = 0.0004 for ?-carotene). There was no association with retinol or cryptoxanthin intake and neovascular AMD (P = 0.67, 0.06).
Source Title: Scientific Reports
URI: https://scholarbank.nus.edu.sg/handle/10635/182507
ISSN: 2045-2322
DOI: 10.1038/srep20723
Rights: Attribution 4.0 International
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1038_srep20723.pdf544.49 kBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

33
checked on Jan 20, 2021

Page view(s)

19
checked on Jan 21, 2021

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons