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https://doi.org/10.3201/eid1301.020112
Title: | Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore | Authors: | Chan, K.P Goh, K.T Chong, C.Y Teo, E.S Lau, G Ling, A.E |
Keywords: | adolescent adult age distribution aged article child child care diagnostic value disease association disease severity early diagnosis Enterovirus epidemic female hand foot and mouth disease health care planning human human enterovirus 71 incidence infant infection control interstitial pneumonia major clinical study male myocarditis newborn seasonal variation Singapore virus culture virus encephalitis virus isolation |
Issue Date: | 2003 | Publisher: | Centers for Disease Control and Prevention (CDC) | Citation: | Chan, K.P, Goh, K.T, Chong, C.Y, Teo, E.S, Lau, G, Ling, A.E (2003). Epidemic hand, foot and mouth disease caused by human enterovirus 71, Singapore. Emerging Infectious Diseases 9 (1) : 78-85. ScholarBank@NUS Repository. https://doi.org/10.3201/eid1301.020112 | Rights: | Attribution 4.0 International | Abstract: | Singapore experienced a large epidemic of hand, foot and mouth disease (HFMD) in 2000. After reviewing HFMD notifications from doctors and child-care centers, we found that the incidence of HFMD rose in September and declined at the end of October. During this period, 3,790 cases were reported. We performed enteroviral cultures on 311 and 157 specimens from 175 HFMD patients and 107 non-HFMD patients, respectively; human enterovirus 71 (HEV71) was the most frequently isolated virus from both groups. Most of the HFMD patients were ?4 years of age. Three HFMD and two non-HFMD patients died. Specimens from two HFMD and both non-HFMD patients were culture positive for HEV71; a third HFMD patient was possibly associated with the virus. Autopsies performed on all three HFMD and one of the non-HFMD case-patients showed encephalitis, interstitial pneumonitis, and myocarditis. A preparedness plan for severe HFMD outbreaks provided for the prompt, coordinated actions needed to control the epidemic. | Source Title: | Emerging Infectious Diseases | URI: | https://scholarbank.nus.edu.sg/handle/10635/181129 | ISSN: | 10806040 | DOI: | 10.3201/eid1301.020112 | Rights: | Attribution 4.0 International |
Appears in Collections: | Elements Staff Publications |
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