Please use this identifier to cite or link to this item: https://doi.org/10.3201/eid1202.050274
Title: Ophthalmic complications of dengue: The eye institute dengue-related ophthalmic complications workgroup
Authors: Chan, D.P.L
Teoh, S.C.B.
Tan, C.S.H.
Nah, G.K.M.
Rajagopalan, R.
Prabhakaragupta, M.K.
Chee, C.K.L.
Lim, T.H.
Goh, K.Y. 
Keywords: adult
article
autoanalyzer
bleeding
central scotoma
clinical article
dengue
eye disease
female
fluorescence angiography
human
iridocyclitis
male
optical coherence tomography
retina detachment
retina macula edema
retina vasculitis
retinopathy
retrospective study
Singapore
thrombocytopenia
visual acuity
visual field
visual impairment
Issue Date: 2006
Publisher: Centers for Disease Control and Prevention (CDC)
Citation: Chan, D.P.L, Teoh, S.C.B., Tan, C.S.H., Nah, G.K.M., Rajagopalan, R., Prabhakaragupta, M.K., Chee, C.K.L., Lim, T.H., Goh, K.Y. (2006). Ophthalmic complications of dengue: The eye institute dengue-related ophthalmic complications workgroup. Emerging Infectious Diseases 12 (2) : 285-289. ScholarBank@NUS Repository. https://doi.org/10.3201/eid1202.050274
Rights: Attribution 4.0 International
Abstract: We report 13 cases of ophthalmic complications resulting from dengue infection in Singapore. We performed a retrospective analysis of a series of 13 patients with dengue fever who had visual impairment. Investigations included Humphrey automated visual field analyzer, Amsler charting, fundus fluorescein angiography, and optical coherence tomography. Twenty-two eyes of 13 patients were affected. The mean age of patients was 31.7 years. Visual acuity varied from 20/25 to counting fingers only. Twelve patients (92.3%) noted central vision impairment. Onset of visual impairment coincided with the nadir of serum thrombocytopenia. Ophthalmologic findings include macular edema and blot hemorrhages (10), cotton wool spots (1), retinal vasculitis (4), exudative retinal detachment (2), and anterior uveitis (1). All patients recovered visual acuity to 20/30 or better with residual central scotoma by 12 weeks. These new complications suggest a widening spectrum of ophthalmic complications in dengue infection.
Source Title: Emerging Infectious Diseases
URI: https://scholarbank.nus.edu.sg/handle/10635/181084
ISSN: 10806040
DOI: 10.3201/eid1202.050274
Rights: Attribution 4.0 International
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