Please use this identifier to cite or link to this item: https://doi.org/10.3201/eid1802.110962
Title: Unsuspected dengue and acute febrile illness in rural and semi-urban southern Sri Lanka
Authors: Reller, M.E
Bodinayake, C
Nagahawatte, A
Devasiri, V
Kodikara-Arachichi, W
Strouse, J.J
Broadwater, A
Østbye, T 
de Silva, A
Woods, C.W
Keywords: immunoglobulin G
immunoglobulin M
acute phase response
adolescent
adult
article
blood sampling
child
clinical feature
controlled study
dengue
Dengue virus 2
Dengue virus 3
Dengue virus 4
female
fever
follow up
human
major clinical study
male
medical history
preschool child
prospective study
reverse transcription polymerase chain reaction
school child
seroconversion
serodiagnosis
seroprevalence
serotype
Sri Lanka
urban rural difference
virus identification
virus isolation
virus neutralization
Adolescent
Adult
Aged
Antibodies, Viral
Child
Child, Preschool
Cohort Studies
Dengue
Dengue Virus
Female
Fever
Humans
Male
Middle Aged
Molecular Typing
Rural Population
Serotyping
Sri Lanka
Suburban Population
Young Adult
Issue Date: 2012
Citation: Reller, M.E, Bodinayake, C, Nagahawatte, A, Devasiri, V, Kodikara-Arachichi, W, Strouse, J.J, Broadwater, A, Østbye, T, de Silva, A, Woods, C.W (2012). Unsuspected dengue and acute febrile illness in rural and semi-urban southern Sri Lanka. Emerging Infectious Diseases 18 (2) : 256-263. ScholarBank@NUS Repository. https://doi.org/10.3201/eid1802.110962
Rights: Attribution 4.0 International
Abstract: Dengue virus (DENV), a globally emerging cause of undifferentiated fever, has been documented in the heavily urbanized western coast of Sri Lanka since the 1960s. New areas of Sri Lanka are now being affected, and the reported number and severity of cases have increased. To study emerging DENV in southern Sri Lanka, we obtained epidemiologic and clinical data and acuteand convalescent-phase serum samples from patients ?2 years old with febrile illness. We tested paired serum samples for DENV IgG and IgM and serotyped virus by using isolation and reverse transcription PCR. We identified acute DENV infection (serotypes 2, 3, and 4) in 54 (6.3%) of 859 patients. Only 14% of patients had clinically suspected dengue; however, 54% had serologically confirmed acute or past DENV infection. DENV is a major and largely unrecognized cause of fever in southern Sri Lanka, especially in young adults.
Source Title: Emerging Infectious Diseases
URI: https://scholarbank.nus.edu.sg/handle/10635/180844
ISSN: 1080-6040
DOI: 10.3201/eid1802.110962
Rights: Attribution 4.0 International
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_3201_eid1802_110962.pdf193.68 kBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

19
checked on Jan 12, 2021

Page view(s)

23
checked on Jan 14, 2021

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons