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https://doi.org/10.1038/srep09290
DC Field | Value | |
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dc.title | Limbus- Versus Fornix-Based Trabeculectomy for Open-Angle Glaucoma Eyes with Prior Ocular Surgery: The Collaborative Bleb-Related Infection Incidence and Treatment Study | |
dc.contributor.author | Yokota, S | |
dc.contributor.author | Takihara, Y | |
dc.contributor.author | Inatani, M | |
dc.date.accessioned | 2020-10-26T09:09:22Z | |
dc.date.available | 2020-10-26T09:09:22Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Yokota, S, Takihara, Y, Inatani, M (2015). Limbus- Versus Fornix-Based Trabeculectomy for Open-Angle Glaucoma Eyes with Prior Ocular Surgery: The Collaborative Bleb-Related Infection Incidence and Treatment Study. Scientific Reports 5 : 9290. ScholarBank@NUS Repository. https://doi.org/10.1038/srep09290 | |
dc.identifier.issn | 2045-2322 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/180477 | |
dc.description.abstract | We compared the surgical successes of limbus- and fornix-based trabeculectomies in open-angle glaucoma (OAG) eyes that had prior ocular surgery in the Collaborative Bleb-Related Infection Incidence and Treatment Study (CBIITS), Japan. From the 1,098 glaucoma eyes in 34 clinical centers in CBIITS, 195 OAG eyes that had undergone previous trabeculectomy and/or lens extraction were included. Limbus- or fornix-based trabeculectomy with mitomycin C were performed. Surgical failure (IOP ? 21, 18, or 15 mmHg for criterion A, B or C, respectively; <20% decrease from baseline; reoperation for glaucoma; or loss of light perception vision) was counted. There were 106 and 89 eyes treated with limbus- and fornix-based trabeculectomies, respectively. At 3 years, IOP (mean ± SD) was 12.5 ± 5.9 and 14.1 ± 6.4 mmHg and the cumulative probabilities of failure during 3 years were 30.2% and 50.5% for criterion A, 40.3% and 57.4% for criterion B, and 57.9% and 65.8% for criterion C in the limbus- and the fornix-based group, respectively. Fornix-based incisions were associated with surgical failure in Cox-proportional multivariable analysis for criterion A [relative risk (RR) = 1.96], and B [RR = 1.60]. Limbus-based trabeculectomy had a higher probability of success in OAG eyes with prior ocular surgery. © 2015, Nature Publishing Group. All rights reserved. | |
dc.publisher | Nature Publishing Group | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.source | Unpaywall 20201031 | |
dc.subject | aged | |
dc.subject | clinical trial | |
dc.subject | female | |
dc.subject | follow up | |
dc.subject | Glaucoma, Open-Angle | |
dc.subject | human | |
dc.subject | intraocular pressure | |
dc.subject | Kaplan Meier method | |
dc.subject | male | |
dc.subject | middle aged | |
dc.subject | mortality | |
dc.subject | multicenter study | |
dc.subject | procedures | |
dc.subject | trabeculectomy | |
dc.subject | treatment outcome | |
dc.subject | very elderly | |
dc.subject | Aged | |
dc.subject | Aged, 80 and over | |
dc.subject | Female | |
dc.subject | Follow-Up Studies | |
dc.subject | Glaucoma, Open-Angle | |
dc.subject | Humans | |
dc.subject | Intraocular Pressure | |
dc.subject | Kaplan-Meier Estimate | |
dc.subject | Male | |
dc.subject | Middle Aged | |
dc.subject | Trabeculectomy | |
dc.subject | Treatment Outcome | |
dc.type | Article | |
dc.contributor.department | CANCER SCIENCE INSTITUTE OF SINGAPORE | |
dc.description.doi | 10.1038/srep09290 | |
dc.description.sourcetitle | Scientific Reports | |
dc.description.volume | 5 | |
dc.description.page | 9290 | |
dc.published.state | published | |
Appears in Collections: | Elements Staff Publications |
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