Please use this identifier to cite or link to this item: https://doi.org/10.1155/2015/325909
Title: The Role of Power Doppler Ultrasonography as Disease Activity Marker in Rheumatoid Arthritis
Authors: Bhasin, S
Cheung, P.P 
Keywords: C reactive protein
disease modifying antirheumatic drug
gadolinium
gelatinase B
stromelysin
tissue inhibitor of metalloproteinase 1
vasculotropin
arthropathy
bone erosion
clinical assessment
DAS28
disease activity
disease marker
Doppler echography
erythrocyte sedimentation rate
histopathology
human
joint effusion
joint swelling
joint tenderness
nuclear magnetic resonance imaging
outcome assessment
physical examination
power doppler ultrasonography
priority journal
prognosis
quantitative analysis
reliability
remission
Review
rheumatoid arthritis
standardization
synovitis
diagnostic imaging
Doppler ultrasonography
procedures
rheumatoid arthritis
Arthritis, Rheumatoid
Humans
Ultrasonography, Doppler
Issue Date: 2015
Publisher: Hindawi Limited
Citation: Bhasin, S, Cheung, P.P (2015). The Role of Power Doppler Ultrasonography as Disease Activity Marker in Rheumatoid Arthritis. Disease Markers 2015 : 325909. ScholarBank@NUS Repository. https://doi.org/10.1155/2015/325909
Rights: Attribution 4.0 International
Abstract: Structural damage in rheumatoid arthritis (RA) occurs early if inflammation is not treated promptly. Treatment targeted to reduce inflammation, in particular, that of synovial inflammation in the joints (synovitis), has been recommended as standard treat-to-target recommendations by rheumatologists. The goal is to achieve disease remission (i.e., no disease activity). Several accepted remission criteria have not always equated to the complete absence of true inflammation. Over the last decade, musculoskeletal ultrasonography has been demonstrated to detect subclinical synovitis not appreciated by routine clinical or laboratory assessments, with the Power Doppler modality allowing clinicians to more readily appreciate true inflammation. Thus, targeting therapy to Power Doppler activity may provide superior outcomes compared with treating to clinical targets alone, making it an attractive marker of disease activity in RA. However, more validation on its true benefits such as its benefits to patients in regard to patient related outcomes and issues with standardized training in acquisition and interpretation of power Doppler findings are required. Copyright © 2015 Shaloo Bhasin and Peter P. Cheung.
Source Title: Disease Markers
URI: https://scholarbank.nus.edu.sg/handle/10635/180116
ISSN: 0278-0240
DOI: 10.1155/2015/325909
Rights: Attribution 4.0 International
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