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https://doi.org/10.1007/s10654-015-0105-7
| Title: | The Rotterdam Scan Study: design update 2016 and main findings | Authors: | Ikram, M.A van der Lugt, A Niessen, W.J Koudstaal, P.J Krestin, G.P Hofman, A Bos, D Vernooij, M.W |
Keywords: | Article brain blood flow brain tissue cerebrovascular disease cohort analysis connectome diffusion tensor imaging disease classification functional magnetic resonance imaging genetics human image analysis image processing image quality incidental finding neuroimaging neurologic disease nuclear magnetic resonance imaging practice guideline resting state network structure analysis white matter white matter lesion aged aging brain brain artery brain mapping chronic disease computer assisted diagnosis female health survey human image processing longitudinal study male middle aged Nervous System Diseases Netherlands neuroimaging nuclear magnetic resonance imaging pathology pathophysiology procedures prospective study risk factor vascularization very elderly Aged Aged, 80 and over Aging Brain Brain Mapping Cerebral Arteries Chronic Disease Female Humans Image Interpretation, Computer-Assisted Image Processing, Computer-Assisted Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged Nervous System Diseases Netherlands Neuroimaging Population Surveillance Prospective Studies Risk Factors |
Issue Date: | 2015 | Publisher: | Springer Netherlands | Citation: | Ikram, M.A, van der Lugt, A, Niessen, W.J, Koudstaal, P.J, Krestin, G.P, Hofman, A, Bos, D, Vernooij, M.W (2015). The Rotterdam Scan Study: design update 2016 and main findings. European Journal of Epidemiology 30 (12) : 1299-1315. ScholarBank@NUS Repository. https://doi.org/10.1007/s10654-015-0105-7 | Rights: | Attribution 4.0 International | Abstract: | Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random subsamples of participants from the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. Moreover, we describe the imaging protocol, image post-processing techniques, and the main findings to date. Finally, we provide recommendations for future research, which will also be topics of investigation in the Rotterdam Scan Study. © 2015, The Author(s). | Source Title: | European Journal of Epidemiology | URI: | https://scholarbank.nus.edu.sg/handle/10635/179636 | ISSN: | 0393-2990 | DOI: | 10.1007/s10654-015-0105-7 | Rights: | Attribution 4.0 International |
| Appears in Collections: | Staff Publications Elements |
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