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https://doi.org/10.1038/s41467-018-06894-8
| Title: | Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease | Authors: | Ackers-Johnson, M Tan, W.L.W Foo, R.S.-Y |
Keywords: | transcription factor Nrf2 untranslated RNA cardiac muscle cell communication cell cycle cell regeneration cells by body anatomy DNA library fluorescence activated cell sorting gene expression gene regulatory network heart development heart disease heart function heart tissue heart work marker gene mouse nonhuman Note quality control RNA sequence single cell RNA sequence transcriptomics aging animal genetics heart disease human pathology procedures sequence analysis single cell analysis Aging Animals Heart Diseases Humans Myocardium Sequence Analysis, RNA Single-Cell Analysis |
Issue Date: | 2018 | Publisher: | Nature Publishing Group | Citation: | Ackers-Johnson, M, Tan, W.L.W, Foo, R.S.-Y (2018). Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease. Nature Communications 9 (1) : 4434. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-018-06894-8 | Rights: | Attribution 4.0 International | Abstract: | The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression networks that regulate the workings, and failings, of the heart. © 2018, The Author(s). | Source Title: | Nature Communications | URI: | https://scholarbank.nus.edu.sg/handle/10635/178387 | ISSN: | 2041-1723 | DOI: | 10.1038/s41467-018-06894-8 | Rights: | Attribution 4.0 International |
| Appears in Collections: | Staff Publications Elements |
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