Please use this identifier to cite or link to this item: https://doi.org/10.1186/1752-1947-2-387
Title: Herpes simplex 1 encephalitis presenting as a brain haemorrhage with normal cerebrospinal fluid analysis: A case report
Authors: Gkrania-Klotsas, E
Lever, A.M.L 
Keywords: aciclovir
ceftriaxone
doxycycline
levofloxacin
virus DNA
adult
article
blood culture
brain hemorrhage
case report
cerebrospinal fluid analysis
clinical feature
computer assisted tomography
herpes simplex encephalitis
Herpes simplex virus 1
hospital admission
hospital discharge
human
lumbar puncture
male
neuroimaging
nuclear magnetic resonance imaging
patient referral
patient transport
polymerase chain reaction
priority journal
urinalysis
urinary tract infection
Issue Date: 2008
Publisher: BMC
Citation: Gkrania-Klotsas, E, Lever, A.M.L (2008). Herpes simplex 1 encephalitis presenting as a brain haemorrhage with normal cerebrospinal fluid analysis: A case report. Journal of Medical Case Reports 2 : 387. ScholarBank@NUS Repository. https://doi.org/10.1186/1752-1947-2-387
Rights: Attribution 4.0 International
Abstract: Introduction: Herpes simplex encephalitis is a potentially lethal infection that should be recognised as soon as possible. The combination of clinical history and examination, brain computed tomography or magnetic resonance imaging and lumbar puncture has been used to establish a diagnosis. Case presentation: We present a patient who had a suggestive history but a totally normal lumbar puncture and only evidence of intracerebral haemorrhage in the brain magnetic resonance imaging. Diagnosis was made by using the cerebrospinal fluid polymerase chain reaction for herpes simplex virus. Conclusion: Herpes simplex encephalitis is being increasingly diagnosed with the availability of new diagnostic techniques. Herpes simplex encephalitis can present with the combination of haemorrhage and normal cerebrospinal fluid. Awareness of this common but, if left untreated, devastating condition should increase. © 2008 Gkrania-Klotsas and Lever; licensee BioMed Central Ltd.
Source Title: Journal of Medical Case Reports
URI: https://scholarbank.nus.edu.sg/handle/10635/178229
ISSN: 1752-1947
DOI: 10.1186/1752-1947-2-387
Rights: Attribution 4.0 International
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