Please use this identifier to cite or link to this item: https://doi.org/10.3389/fpls.2018.00972
Title: Arabidopsis serine decarboxylase 1 (SDC1) in phospholipid and amino acid metabolism
Authors: Liu, Y.-C 
Gunawan, F
Yunus, I.S
Nakamura, Y
Issue Date: 2018
Citation: Liu, Y.-C, Gunawan, F, Yunus, I.S, Nakamura, Y (2018). Arabidopsis serine decarboxylase 1 (SDC1) in phospholipid and amino acid metabolism. Frontiers in Plant Science 9 : 972. ScholarBank@NUS Repository. https://doi.org/10.3389/fpls.2018.00972
Rights: Attribution 4.0 International
Abstract: Arabidopsis thaliana serine decarboxylase 1 (SDC1) catalyzes conversion of serine to ethanolamine, the first reaction step of phosphatidylcholine and phosphatidylethanolamine biosynthesis. However, an involvement of SDC1 in amino acid metabolism remains elusive despite that serine is the substrate of SDC1. Here, we showed that SDC1 localizes in mitochondria although phosphatidylcholine and phosphatidylethanolamine are known to be produced in the endoplasmic reticulum (ER). Moreover, we found that overexpression of SDC1 decreased levels of amino acid compounds derived from mitochondrial tricarboxylic acid cycle. These results suggest that mitochondria-localized SDC1 plays an important role in both phospholipid and amino acid metabolism in A. thaliana. © 2018 Liu, Gunawan, Yunus and Nakamura.
Source Title: Frontiers in Plant Science
URI: https://scholarbank.nus.edu.sg/handle/10635/178075
ISSN: 1664462X
DOI: 10.3389/fpls.2018.00972
Rights: Attribution 4.0 International
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_3389_fpls_2018_00972.pdf2.3 MBAdobe PDF

OPEN

NoneView/Download

Google ScholarTM

Check

Altmetric


This item is licensed under a Creative Commons License Creative Commons