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https://doi.org/10.1186/1471-2156-10-80
Title: | Genomic microsatellites identify shared Jewish ancestry intermediate between Middle Eastern and European populations | Authors: | Kopelman, N.M Stone, L Wang, C Gefel, D Feldman, M.W Hillel, J Rosenberg, N.A |
Keywords: | article Bayes theorem Caucasian controlled study gene locus genetic analysis genetic similarity genetic variability geography heterozygosity human human cell jew microsatellite marker Middle East neighbor joining method normal human population genetics population structure ethnology Europe genetics human genome jew population genetics microsatellite DNA Europe Genetics, Population Genome, Human Humans Jews Microsatellite Repeats Middle East |
Issue Date: | 2009 | Citation: | Kopelman, N.M, Stone, L, Wang, C, Gefel, D, Feldman, M.W, Hillel, J, Rosenberg, N.A (2009). Genomic microsatellites identify shared Jewish ancestry intermediate between Middle Eastern and European populations. BMC Genetics 10 : 80. ScholarBank@NUS Repository. https://doi.org/10.1186/1471-2156-10-80 | Rights: | Attribution 4.0 International | Abstract: | Background: Genetic studies have often produced conflicting results on the question of whether distant Jewish populations in different geographic locations share greater genetic similarity to each other or instead, to nearby non-Jewish populations. We perform a genome-wide population-genetic study of Jewish populations, analyzing 678 autosomal microsatellite loci in 78 individuals from four Jewish groups together with similar data on 321 individuals from 12 non-Jewish Middle Eastern and European populations. Results: We find that the Jewish populations show a high level of genetic similarity to each other, clustering together in several types of analysis of population structure. Further, Bayesian clustering, neighbor-joining trees, and multidimensional scaling place the Jewish populations as intermediate between the non-Jewish Middle Eastern and European populations. Conclusion: These results support the view that the Jewish populations largely share a common Middle Eastern ancestry and that over their history they have undergone varying degrees of admixture with non-Jewish populations of European descent. © 2009 Kopelman et al; licensee BioMed Central Ltd. | Source Title: | BMC Genetics | URI: | https://scholarbank.nus.edu.sg/handle/10635/177942 | ISSN: | 14712156 | DOI: | 10.1186/1471-2156-10-80 | Rights: | Attribution 4.0 International |
Appears in Collections: | Elements Staff Publications |
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