Please use this identifier to cite or link to this item: https://doi.org/10.1186/1471-2156-10-80
Title: Genomic microsatellites identify shared Jewish ancestry intermediate between Middle Eastern and European populations
Authors: Kopelman, N.M
Stone, L
Wang, C 
Gefel, D
Feldman, M.W
Hillel, J
Rosenberg, N.A
Keywords: article
Bayes theorem
Caucasian
controlled study
gene locus
genetic analysis
genetic similarity
genetic variability
geography
heterozygosity
human
human cell
jew
microsatellite marker
Middle East
neighbor joining method
normal human
population genetics
population structure
ethnology
Europe
genetics
human genome
jew
population genetics
microsatellite DNA
Europe
Genetics, Population
Genome, Human
Humans
Jews
Microsatellite Repeats
Middle East
Issue Date: 2009
Citation: Kopelman, N.M, Stone, L, Wang, C, Gefel, D, Feldman, M.W, Hillel, J, Rosenberg, N.A (2009). Genomic microsatellites identify shared Jewish ancestry intermediate between Middle Eastern and European populations. BMC Genetics 10 : 80. ScholarBank@NUS Repository. https://doi.org/10.1186/1471-2156-10-80
Rights: Attribution 4.0 International
Abstract: Background: Genetic studies have often produced conflicting results on the question of whether distant Jewish populations in different geographic locations share greater genetic similarity to each other or instead, to nearby non-Jewish populations. We perform a genome-wide population-genetic study of Jewish populations, analyzing 678 autosomal microsatellite loci in 78 individuals from four Jewish groups together with similar data on 321 individuals from 12 non-Jewish Middle Eastern and European populations. Results: We find that the Jewish populations show a high level of genetic similarity to each other, clustering together in several types of analysis of population structure. Further, Bayesian clustering, neighbor-joining trees, and multidimensional scaling place the Jewish populations as intermediate between the non-Jewish Middle Eastern and European populations. Conclusion: These results support the view that the Jewish populations largely share a common Middle Eastern ancestry and that over their history they have undergone varying degrees of admixture with non-Jewish populations of European descent. © 2009 Kopelman et al; licensee BioMed Central Ltd.
Source Title: BMC Genetics
URI: https://scholarbank.nus.edu.sg/handle/10635/177942
ISSN: 14712156
DOI: 10.1186/1471-2156-10-80
Rights: Attribution 4.0 International
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