Please use this identifier to cite or link to this item: https://doi.org/10.1111/sms.13015
Title: Neural basis of exertional fatigue in the heat: A review of magnetic resonance imaging methods
Authors: Tan X.R.
Low I.C.C. 
Stephenson M.C.
Soong T.W. 
Lee J.K.W. 
Keywords: brain
central fatigue
exercise
hyperthermia
hypohydration
magnetic resonance imaging
neuroimaging
Issue Date: 2018
Publisher: Blackwell Munksgaard
Citation: Tan X.R., Low I.C.C., Stephenson M.C., Soong T.W., Lee J.K.W. (2018). Neural basis of exertional fatigue in the heat: A review of magnetic resonance imaging methods. Scandinavian Journal of Medicine and Science in Sports 28 (3) : 807 - 818. ScholarBank@NUS Repository. https://doi.org/10.1111/sms.13015
Abstract: The central nervous system, specifically the brain, is implicated in the development of exertional fatigue under a hot environment. Diverse neuroimaging techniques have been used to visualize the brain activity during or after exercise. Notably, the use of magnetic resonance imaging (MRI) has become prevalent due to its excellent spatial resolution and versatility. This review evaluates the significance and limitations of various brain MRI techniques in exercise studies?brain volumetric analysis, functional MRI, functional connectivity MRI, and arterial spin labeling. The review aims to provide a summary on the neural basis of exertional fatigue and proposes future directions for brain MRI studies. A systematic literature search was performed where a total of thirty-seven brain MRI studies associated with exercise, fatigue, or related physiological factors were reviewed. The findings suggest that with moderate dehydration, there is a decrease in total brain volume accompanied with expansion of ventricular volume. With exercise fatigue, there is increased activation of sensorimotor and cognitive brain areas, increased thalamo-insular activation and decreased interhemispheric connectivity in motor cortex. Under passive hyperthermia, there are regional changes in cerebral perfusion, a reduction in local connectivity in functional brain networks and an impairment to executive function. Current literature suggests that the brain structure and function are influenced by exercise, fatigue, and related physiological perturbations. However, there is still a dearth of knowledge and it is hoped that through understanding of MRI advantages and limitations, future studies will shed light on the central origin of exertional fatigue in the heat. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Source Title: Scandinavian Journal of Medicine and Science in Sports
URI: https://scholarbank.nus.edu.sg/handle/10635/177611
ISSN: 09057188
DOI: 10.1111/sms.13015
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

4
checked on Jan 25, 2023

WEB OF SCIENCETM
Citations

4
checked on Oct 5, 2021

Page view(s)

181
checked on Jan 26, 2023

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.