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|Title:||Associations of physical activity levels and screen time with oral glucose tolerance test profiles in Singaporean women of reproductive age actively trying to conceive: the S-PRESTO study||Authors:||Bernard J.Y.
|Issue Date:||2019||Publisher:||Blackwell Publishing Ltd||Citation:||Bernard J.Y., Ng S., Natarajan P., Loy S.L., Aris I.M., Tint M.T., Chong Y.-S., Shek L., Chan J., Godfrey K.M., Khoo C.M., Leow M.K.-S., Müller-Riemenschneider F., Chan S.-Y. (2019). Associations of physical activity levels and screen time with oral glucose tolerance test profiles in Singaporean women of reproductive age actively trying to conceive: the S-PRESTO study. Diabetic Medicine 36 (7) : 888 - 897. ScholarBank@NUS Repository. https://doi.org/10.1111/dme.13948||Abstract:||Aim: To examine the associations of physical activity and screen time, a proxy for sedentary behaviour, with fasting and post-load glucose levels in Singaporean women enrolled in a multi-ethnic Asian preconception study. Methods: Moderate and vigorous physical activity and screen time (television and other electronic devices) were self-reported by women enrolled in the S-PRESTO cohort. Fasting, 30-min and 120-min glucose levels before and during a 75-g oral glucose tolerance test were measured. Associations of physical activity and screen time with glucose levels were analysed using multivariable linear marginal regression. Results: A total of 946 women aged 31.4±3.7 years were examined, of whom 72% were of Chinese, 15.5% were of Malay, 9.3% were of Indian and 3.2% were of mixed ethnicity. A total of 32% of women reported being active, 36% watched television ≥2 h/day and 26% used electronic devices ≥3 h/day. In adjusted models, vigorous, but not moderate, physical activity was associated with lower overall glucose levels, and was associated more strongly with post-challenge than fasting glucose levels. Compared to women not engaging in vigorous physical activity, those engaging in physical activity ≥75 min/week had lower mean fasting [–0.14 (95% CI –0.28, –0.01) mmol/l], 30-min [0.35 (95% CI –0.68, –0.02) mmol/l] and 120-min [–0.53 (95% CI –0.16, –0.90) mmol/l] glucose levels (overall P value=0.05). We found no associations of screen time with glucose levels. Conclusions: Independently of the time spent in non-vigorous physical activity and using screens, engaging in vigorous physical activity may be a modifiable factor to improve glucose regulation in women of Asian ethnicity who are attempting to conceive. © 2019 Diabetes UK||Source Title:||Diabetic Medicine||URI:||https://scholarbank.nus.edu.sg/handle/10635/177463||ISSN:||07423071||DOI:||10.1111/dme.13948|
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