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Title: A 3D Printed Implantable Device for Voiding the Bladder Using Shape Memory Alloy (SMA) Actuators
Authors: Hassani, F.A 
Peh, W.Y.X 
Gammad, G.G.L
Mogan, R.P 
Ng, T.K
Kuo, T.L.C 
Ng, L.G 
Luu, P 
Yen, S.-C 
Lee, C 
Issue Date: 2017
Citation: Hassani, F.A, Peh, W.Y.X, Gammad, G.G.L, Mogan, R.P, Ng, T.K, Kuo, T.L.C, Ng, L.G, Luu, P, Yen, S.-C, Lee, C (2017). A 3D Printed Implantable Device for Voiding the Bladder Using Shape Memory Alloy (SMA) Actuators. Advanced Science 4 (11) : 1700143. ScholarBank@NUS Repository.
Abstract: Underactive bladder or detrusor underactivity (DU) is defined as a reduction of contraction strength or duration of the bladder wall. Despite the serious healthcare implications of DU, there are limited solutions for affected individuals. A flexible 3D printed implantable device driven by shape memory alloys (SMA) actuators is presented here for the first time to physically contract the bladder to restore voluntary control of the bladder for individuals suffering from DU. This approach is used initially in benchtop experiments with a rubber balloon acting as a model for the rat bladder to verify its potential for voiding, and that the operating temperatures are safe for the eventual implantation of the device in a rat. The device is then implanted and tested on an anesthetized rat, and a voiding volume of more than 8% is successfully achieved for the SMA-based device without any surgical intervention or drug injection to relax the external sphincter. © 2017 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Advanced Science
ISSN: 2198-3844
DOI: 10.1002/advs.201700143
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