Please use this identifier to cite or link to this item: https://doi.org/10.1194/jlr.M079012
Title: Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma
Authors: Bowden, John A
Heckert, Alan
Ulmer, Candice Z
Jones, Christina M
Koelmel, Jeremy P
Abdullah, Laila
Ahonen, Linda
Alnouti, Yazen
Armando, Aaron M
Asara, John M
Bamba, Takeshi
Barr, John R
Bergquist, Jonas
Borchers, Christoph H
Brandsma, Joost
Breitkopf, Susanne B
Cajka, Tomas
Cazenave-Gassiot, Amaury 
Checa, Antonio
Cinel, Michelle A
Colas, Romain A
Cremers, Serge
Dennis, Edward A
Evans, James E
Fauland, Alexander
Fiehn, Oliver
Gardner, Michael S
Garrett, Timothy J
Gotlinger, Katherine H
Han, Jun
Huang, Yingying
Neo, Aveline Huipeng
Hyotylainen, Tuulia
Izumi, Yoshihiro
Jiang, Hongfeng
Jiang, Houli
Jiang, Jiang
Kachman, Maureen
Kiyonami, Reiko
Klavins, Kristaps
Klose, Christian
Kofeler, Harald C
Kolmert, Johan
Koal, Therese
Koster, Grielof
Kuklenyik, Zsuzsanna
Kurland, Irwin J
Leadley, Michael
Lin, Karen
Maddipati, Krishna Rao
McDougall, Danielle
Meikle, Peter J
Mellett, Natalie A
Monnin, Cian
Moseley, M Arthur
Nandakumar, Renu
Oresic, Matej
Patterson, Rainey
Peake, David
Pierce, Jason S
Post, Martin
Postle, Anthony D
Pugh, Rebecca
Qiu, Yunping
Quehenberger, Oswald
Ramrup, Parsram
Rees, Jon
Rembiesa, Barbara
Reynaud, Denis
Roth, Mary R
Sales, Susanne
Schuhmann, Kai
Schwartzman, Michal Laniado
Serhan, Charles N
Shevchenko, Andrej
Somerville, Stephen E
John-Williams, Lisa St
Surma, Michal A
Takeda, Hiroaki
Thakare, Rhishikesh
Thompson, J Will
Torta, Federico
Triebl, Alexander
Troetzmueller, Martin
Ubhayasekera, SJ Kumari
Vuckovic, Dajana
Weir, Jacquelyn M
Welti, Ruth
Wenk, Markus R
Wheelock, Craig E
Yao, Libin
Yuan, Min
Zhao, Xueqing Heather
Zhou, Senlin
Keywords: Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
fatty acyls
glycerolipids
lipids
phospholipids
quality control
quantitation
sphingolipids
Standard Reference Material 1950
sterols
National Institute of Standards and Technology
IONIZATION MASS-SPECTROMETRY
STANDARD REFERENCE MATERIAL
CHOLESTEROL CONTROVERSY
TARGETED METABOLOMICS
INTERPRETIVE HISTORY
REPORTING STANDARDS
PRECISION MEDICINE
HIGH-THROUGHPUT
LC-MS
DISEASE
Issue Date: 2017
Publisher: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Citation: Bowden, John A, Heckert, Alan, Ulmer, Candice Z, Jones, Christina M, Koelmel, Jeremy P, Abdullah, Laila, Ahonen, Linda, Alnouti, Yazen, Armando, Aaron M, Asara, John M, Bamba, Takeshi, Barr, John R, Bergquist, Jonas, Borchers, Christoph H, Brandsma, Joost, Breitkopf, Susanne B, Cajka, Tomas, Cazenave-Gassiot, Amaury, Checa, Antonio, Cinel, Michelle A, Colas, Romain A, Cremers, Serge, Dennis, Edward A, Evans, James E, Fauland, Alexander, Fiehn, Oliver, Gardner, Michael S, Garrett, Timothy J, Gotlinger, Katherine H, Han, Jun, Huang, Yingying, Neo, Aveline Huipeng, Hyotylainen, Tuulia, Izumi, Yoshihiro, Jiang, Hongfeng, Jiang, Houli, Jiang, Jiang, Kachman, Maureen, Kiyonami, Reiko, Klavins, Kristaps, Klose, Christian, Kofeler, Harald C, Kolmert, Johan, Koal, Therese, Koster, Grielof, Kuklenyik, Zsuzsanna, Kurland, Irwin J, Leadley, Michael, Lin, Karen, Maddipati, Krishna Rao, McDougall, Danielle, Meikle, Peter J, Mellett, Natalie A, Monnin, Cian, Moseley, M Arthur, Nandakumar, Renu, Oresic, Matej, Patterson, Rainey, Peake, David, Pierce, Jason S, Post, Martin, Postle, Anthony D, Pugh, Rebecca, Qiu, Yunping, Quehenberger, Oswald, Ramrup, Parsram, Rees, Jon, Rembiesa, Barbara, Reynaud, Denis, Roth, Mary R, Sales, Susanne, Schuhmann, Kai, Schwartzman, Michal Laniado, Serhan, Charles N, Shevchenko, Andrej, Somerville, Stephen E, John-Williams, Lisa St, Surma, Michal A, Takeda, Hiroaki, Thakare, Rhishikesh, Thompson, J Will, Torta, Federico, Triebl, Alexander, Troetzmueller, Martin, Ubhayasekera, SJ Kumari, Vuckovic, Dajana, Weir, Jacquelyn M, Welti, Ruth, Wenk, Markus R, Wheelock, Craig E, Yao, Libin, Yuan, Min, Zhao, Xueqing Heather, Zhou, Senlin (2017). Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma. JOURNAL OF LIPID RESEARCH 58 (12) : 2275-2288. ScholarBank@NUS Repository. https://doi.org/10.1194/jlr.M079012
Abstract: Copyright © 2017 by the American Society for Biochemistry and Molecular Biology, Inc. As the lipidomics field continues to advance, self-evaluation within the community is critical. Here, we performed an interlaboratory comparison exercise for lipidomics using Standard Reference Material (SRM) 1950- Metabolites in Frozen Human Plasma, a commercially available reference material. The interlaboratory study comprised 31 diverse laboratories, with each laboratory using a different lipidomics workflow. A total of 1,527 unique lipids were measured across all laboratories and consensus location estimates and associated uncertainties were determined for 339 of these lipids measured at the sum composition level by five or more participating laboratories. These evaluated lipids detected in SRM 1950 serve as community-wide benchmarks for intra-And interlaboratory quality control and method validation. These analyses were performed using nonstandardized laboratory-independent workflows. The consensus locations were also compared with a previous examination of SRM 1950 by the LIPID MAPS consortium. While the central theme of the interlaboratory study was to provide values to help harmonize lipids, lipid mediators, and precursor measurements across the community, it was also initiated to stimulate a discussion regarding areas in need of improvement.
Source Title: JOURNAL OF LIPID RESEARCH
URI: https://scholarbank.nus.edu.sg/handle/10635/170493
ISSN: 00222275
15397262
DOI: 10.1194/jlr.M079012
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