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https://doi.org/10.1371/journal.pone.0030333
DC Field | Value | |
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dc.title | Systematic review of economic evaluations of preparedness strategies and interventions against influenza pandemics | |
dc.contributor.author | Velasco R.P. | |
dc.contributor.author | Praditsitthikorn N. | |
dc.contributor.author | Wichmann K. | |
dc.contributor.author | Mohara A. | |
dc.contributor.author | Kotirum S. | |
dc.contributor.author | Tantivess S. | |
dc.contributor.author | Vallenas C. | |
dc.contributor.author | Harmanci H. | |
dc.contributor.author | Teerawattananon Y. | |
dc.date.accessioned | 2020-03-18T05:46:34Z | |
dc.date.available | 2020-03-18T05:46:34Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Velasco R.P., Praditsitthikorn N., Wichmann K., Mohara A., Kotirum S., Tantivess S., Vallenas C., Harmanci H., Teerawattananon Y. (2012). Systematic review of economic evaluations of preparedness strategies and interventions against influenza pandemics. PLoS ONE 7 (2) : e30333. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0030333 | |
dc.identifier.issn | 19326203 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/165577 | |
dc.description.abstract | Background: Although public health guidelines have implications for resource allocation, these issues were not explicitly considered in previous WHO pandemic preparedness and response guidance. In order to ensure a thorough and informed revision of this guidance following the H1N1 2009 pandemic, a systematic review of published and unpublished economic evaluations of preparedness strategies and interventions against influenza pandemics was conducted. Methods: The search was performed in September 2011 using 10 electronic databases, 2 internet search engines, reference list screening, cited reference searching, and direct communication with relevant authors. Full and partial economic evaluations considering both costs and outcomes were included. Conversely, reviews, editorials, and studies on economic impact or complications were excluded. Studies were selected by 2 independent reviewers. Results: 44 studies were included. Although most complied with the cost effectiveness guidelines, the quality of evidence was limited. However, the data sources used were of higher quality in economic evaluations conducted after the 2009 H1N1 pandemic. Vaccination and drug regimens were varied. Pharmaceutical plus non-pharmaceutical interventions are relatively cost effective in comparison to vaccines and/or antivirals alone. Pharmaceutical interventions vary from cost saving to high cost effectiveness ratios. According to ceiling thresholds (Gross National Income per capita), the reduction of non-essential contacts and the use of pharmaceutical prophylaxis plus the closure of schools are amongst the cost effective strategies for all countries. However, quarantine for household contacts is not cost effective even for low and middle income countries. Conclusion: The available evidence is generally inconclusive regarding the cost effectiveness of preparedness strategies and interventions against influenza pandemics. Studies on their effectiveness and cost effectiveness should be readily implemented in forthcoming events that also involve the developing world. Guidelines for assessing the impact of disease and interventions should be drawn up to facilitate these studies. © 2012 World Health Organization; licensee Public Library of Science (PLoS). | |
dc.publisher | Public Library of Science | |
dc.source | Unpaywall 20200320 | |
dc.subject | control strategy | |
dc.subject | cost control | |
dc.subject | cost effectiveness analysis | |
dc.subject | economic evaluation | |
dc.subject | health care cost | |
dc.subject | human | |
dc.subject | infection control | |
dc.subject | infection prevention | |
dc.subject | influenza vaccination | |
dc.subject | pandemic influenza | |
dc.subject | practice guideline | |
dc.subject | review | |
dc.subject | systematic review | |
dc.subject | cost benefit analysis | |
dc.subject | disaster planning | |
dc.subject | economics | |
dc.subject | infectious disease medicine | |
dc.subject | influenza | |
dc.subject | Influenza virus A H1N1 | |
dc.subject | information processing | |
dc.subject | metabolism | |
dc.subject | methodology | |
dc.subject | pandemic | |
dc.subject | public health | |
dc.subject | statistical analysis | |
dc.subject | statistical model | |
dc.subject | Communicable Disease Control | |
dc.subject | Cost-Benefit Analysis | |
dc.subject | Data Collection | |
dc.subject | Data Interpretation, Statistical | |
dc.subject | Disaster Planning | |
dc.subject | Humans | |
dc.subject | Infectious Disease Medicine | |
dc.subject | Influenza A Virus, H1N1 Subtype | |
dc.subject | Influenza, Human | |
dc.subject | Models, Economic | |
dc.subject | Pandemics | |
dc.subject | Public Health | |
dc.type | Review | |
dc.contributor.department | SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH | |
dc.description.doi | 10.1371/journal.pone.0030333 | |
dc.description.sourcetitle | PLoS ONE | |
dc.description.volume | 7 | |
dc.description.issue | 2 | |
dc.description.page | e30333 | |
dc.published.state | Published | |
Appears in Collections: | Elements Staff Publications |
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