Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0053857
Title: Challenges to Evaluating Respiratory Syncytial Virus Mortality in Bangladesh, 2004-2008
Authors: Stockman L.J.
Brooks W.A.
Streatfield P.K.
Rahman M.
Goswami D.
Nahar K.
Rahman M.Z. 
Luby S.P.
Anderson L.J.
Keywords: Adenovirus
article
asthma
autopsy
Bangladesh
cause of death
child
child death
childhood mortality
disease surveillance
epidemic
human
Human metapneumovirus
Influenza virus
lower respiratory tract infection
nasopharyngeal aspiration
nonhuman
Parainfluenza virus 1
Parainfluenza virus 2
Parainfluenza virus 3
pneumonia
preschool child
Respiratory syncytial pneumovirus
respiratory tract disease
reverse transcription polymerase chain reaction
seasonal variation
urban rural difference
virus detection
Adenoviridae
Adenovirus Infections, Human
Adolescent
Bangladesh
Child
Child, Preschool
Female
Humans
Infant
Influenza A virus
Influenza, Human
Male
Metapneumovirus
Parainfluenza Virus 1, Human
Paramyxoviridae Infections
Population Surveillance
Respiratory Syncytial Virus Infections
Respiratory Syncytial Viruses
Retrospective Studies
Seasons
Survival Rate
Urban Population
Adenoviridae
Human metapneumovirus
parainfluenza virus
Respiratory syncytial virus
Rice stripe virus
Issue Date: 2013
Citation: Stockman L.J., Brooks W.A., Streatfield P.K., Rahman M., Goswami D., Nahar K., Rahman M.Z., Luby S.P., Anderson L.J. (2013). Challenges to Evaluating Respiratory Syncytial Virus Mortality in Bangladesh, 2004-2008. PLoS ONE 8 (1) : e53857. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0053857
Abstract: Background: Acute lower respiratory illness is the most common cause of death among children, globally. Data are not available to make accurate estimates on the global mortality from respiratory syncytial virus (RSV), specifically. Methods: Respiratory samples collected from children under 5 years of age during 2004 to 2008 as part of population-based respiratory disease surveillance in an urban community in Dhaka, Bangladesh were tested for RSV, human metapneumovirus (HMPV), human parainfluenza virus (PIV) types 1, 2, and 3, influenza and adenovirus by RT-PCR. Verbal autopsy data were used to identify children who died from respiratory illness in a nearby rural community. Significance of the correlation between detections and community respiratory deaths was determined using Spearman's coefficient. Results: RSV activity occurred during defined periods lasting approximately three months but with no clear seasonal pattern. There was no significant correlation between respiratory deaths and detection of any of the respiratory viruses studied. Conclusion: Outbreaks of respiratory viruses may not be associated with deaths in children in the study site; however, the few respiratory deaths observed and community-to-community variation in the timing of outbreaks may have obscured an association. An accurate assessment of respiratory virus-associated deaths will require detections and death data to come from the same location and a larger study population.
Source Title: PLoS ONE
URI: https://scholarbank.nus.edu.sg/handle/10635/161347
ISSN: 19326203
DOI: 10.1371/journal.pone.0053857
Appears in Collections:Elements
Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
10_1371_journal_pone_0053857.pdf761.21 kBAdobe PDF

OPEN

NoneView/Download

SCOPUSTM   
Citations

15
checked on Sep 13, 2020

Page view(s)

76
checked on Sep 18, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.