Please use this identifier to cite or link to this item:
Title: Track-walking molecular motors: A new generation beyond bridge-burning designs
Authors: Wang, Z 
Hou, R
Loh, IY 
Issue Date: 21-May-2019
Citation: Wang, Z, Hou, R, Loh, IY (2019-05-21). Track-walking molecular motors: A new generation beyond bridge-burning designs. Nanoscale 11 (19) : 9240-9263. ScholarBank@NUS Repository.
Abstract: © 2019 The Royal Society of Chemistry. Track-walking molecular motors are the core bottom-up mechanism for nanometre-resolved translational movements-a fundamental technological capability at the root of numerous applications ranging from nanoscale assembly lines and chemical synthesis to molecular robots and shape-changing materials. Over the last 10 years, artificial molecular walkers (or nanowalkers) have evolved from the 1 st generation of bridge-burning designs to the 2 nd generation capable of truly sustainable movements. Invention of non-bridge-burning nanowalkers was slow at first, but has picked up speed since 2012, and is now close to breaking major barriers for wide-spread development. Here we review the 2 nd generation of artificial nanowalkers, which are mostly made of DNA molecules and draw energy from light illumination or from chemical fuels for entirely autonomous operation. They are typically symmetric dimeric motors walking on entirely periodic tracks, yet the motors possess an inherent direction for large-scale amplification of the action of many motor copies. These translational motors encompass the function of rotational molecular motors on circular or linear tracks, and may involve molecular shuttles as 'engine' motifs. Some rules of thumb are provided to help readers design similar motors from DNA or other molecular building blocks. Opportunities and challenges for future development are discussed, especially in the areas of molecular robotics and active materials based on the advanced motors.
Source Title: Nanoscale
ISSN: 2040-3364
DOI: 10.1039/c9nr00033j
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
2019-NS-review.pdfPublished version4.98 MBAdobe PDF




checked on Nov 28, 2021

Page view(s)

checked on Dec 2, 2021


checked on Dec 2, 2021

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.