Please use this identifier to cite or link to this item: https://doi.org/10.25540/a4ew-pjez
Title: Data from: Changes in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure
Creators: Nadja S. Sieber-Ruckstuhl
Bo Burla 
Susanne Spoerel
Florence Schmid
Claudio Venzin
Amaury Cazenave-Gassiot 
Anne K. Bendt 
Federico Torta 
Markus R. Wenk 
Felicitas S. Boretti
Subject: Lipidomics
Glucocorticoids
Plasma
Mass Spectrometry
DOI: doi:10.25540/a4ew-pjez
Description: 

Glucocorticoids (GCs) are widely used in veterinary and human medicine. Chromic endogenous or iatrogenic GC overexposure impairs metabolic function and can result in diverse side-effects, including Cushing’s syndrome. This study examines the effects of experimentally induced short-term and long-term GC excess (induced by prednisolone and tetracosactide, respectively) on the plasma lipidome of Beale dogs. Both, long- and short-term GC resulted in significant changes of the plasma lipidome.


For more details, please refer to Sieber-Ruckstuhl, N. N. S. et al. (2019). Dataset in Metabolomics Workbench. PR000761: Changes in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure.https://doi.org/10.21228/M89Q32

Related Publications: 10.1038/s41598-019-42190-1
10635/154070
Citation: When using this data, please cite the original publication and also the dataset.
  • Sieber-Ruckstuhl N.S., Burla B., Spoerel S., Schmid F., Venzin C., Cazenave-Gassiot A., Bendt A.K., Torta F., Wenk M. R., and Boretti, F. S. (2019). Changes in the Canine plasma Lipidome after short-and Long-term excess Glucocorticoid exposure. Scientific reports, 9(1), 6015. https://doi.org/10.1038/s41598-019-42190-1
  • Sieber-Ruckstuhl, N. N. S. et al. (2019). Dataset in Metabolomics Workbench. PR000761: Changes in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure.https://doi.org/10.21228/M89Q32
  • Singapore Lipidomics Incubator (2019, March 1. Zenodo), R scripts for: Changes in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure (Version v1.0.0). https://doi.org/10.5281/zenodo.2581113
  • Nadja S. Sieber-Ruckstuhl, Bo Burla, Susanne Spoerel, Florence Schmid, Claudio Venzin, Amaury Cazenave-Gassiot, Anne K. Bendt, Federico Torta, Markus R. Wenk, Felicitas S. Boretti (2019-03-16). Data from: Changes in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure. ScholarBank@NUS Repository. [Dataset]. https://doi.org/10.25540/a4ew-pjez
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R_Codes_v1.0.0.zipR codes used for data analysis and plotting of figures109.52 MBZIP

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ST001140.zipMass spectrometry raw data136.63 MBZIP

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readme.txtreadme file2.45 kBText

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